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Product Name: Choline Chloride
Chemical Formula: C5H14ClNO
CAS Number: 67-48-1
EC Number: 200-655-4
Synonyms: Choline Base, Vitamin B4, Choline Hydroxyethyl Trimethylammonium Chloride
Intended Use: Used as a feed additive, in pharmaceuticals, and as a chemical intermediate
Supplier/Manufacturer Information: [Company’s Address, Phone Number, Emergency Contact Number]
Recommended Restrictions: Not for food or drug use in humans unless otherwise specified
Classification: Not classified as hazardous according to GHS
Physical Hazards: May cause mild irritation to eyes or skin on contact
Health Hazards: Dust inhalation may cause mild respiratory discomfort
Environmental Hazards: Not considered hazardous to the environment under normal use and handling
Signal Word: None required
Hazard Statements: May cause irritation; prolonged or repeated contact can dry skin
Precautionary Statements: Avoid breathing dust; wash exposed skin thoroughly; use protective gloves and eye protection during handling
Substance: Choline Chloride
Chemical Name: Choline Chloride
CAS Number: 67-48-1
Percentage: ≥98%
Impurities/Additives: May contain trace levels of trimethylamine and other related quaternary ammonium compounds from the manufacturing process; individual concentrations usually less than 1%
Inhalation: Move person to fresh air; seek medical attention if symptoms persist
Skin Contact: Rinse skin with soap and water for at least 15 minutes; remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing
Ingestion: Rinse mouth with water; do not induce vomiting; seek medical attention if feeling unwell
Symptoms/Effects: May cause localized irritation to eyes, skin, or respiratory tract depending on exposure route and duration
Advice for Medical Professionals: Treat symptomatically, pay attention to airway, breathing, and circulation
Suitable Extinguishing Media: Water spray, foam, dry powder, carbon dioxide
Unsuitable Extinguishing Media: None known
Specific Hazards: Dust released can form explosive mixtures in air
Hazardous Combustion Products: May emit toxic fumes including nitrogen oxides, hydrogen chloride, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus
Special Precautions: Cool exposed containers with water spray to prevent pressure buildup; avoid inhalation of combustion products
Personal Precautions: Avoid generation and inhalation of dust; wear suitable protective clothing, gloves, and eye/face protection
Environmental Precautions: Prevent entry into waterways, drains, or confined areas
Spill Cleanup Procedures: Sweep up spill and place in labeled containers for recycling or disposal; use non-sparking tools; wash spill area; ventilate if indoors
Methods for Containment: Dike spill with inert material such as sand or earth to prevent runoff
Safe Handling Practices: Use with adequate ventilation; minimize dust generation and accumulation; keep containers tightly closed when not in use
Storage Requirements: Store in a dry, cool, and well-ventilated place; keep away from strong oxidizers and incompatible materials
Packaging Materials: Use strong, moisture-resistant bags or drums; ensure packaging is clearly labeled
Special Precautions: Regularly clean storage area and inspect for leaks or damage; restrict access to authorized personnel only
Occupational Exposure Limits: No specific occupational exposure limits established for choline chloride; follow local regulations
Engineering Controls: Use local exhaust ventilation or process enclosures to minimize dust levels
Respiratory Protection: Approved dust mask or respirator in areas with high airborne concentrations
Skin Protection: Impermeable gloves recommended; wash hands after handling
Eye Protection: Safety goggles or face shield
Other Protective Equipment: Wear long-sleeved lab coats or coveralls; provide eyewash stations and safety showers in work areas
Appearance: White crystalline powder, often with a characteristic fishy odor
Odor: Slight, resembling fish or amine
pH: 5 - 7 (10% solution in water)
Melting Point: 302°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Solubility: Highly soluble in water; soluble in alcohol, insoluble in most organic solvents
Vapor Pressure: Negligible at room temperature
Bulk Density: Approximately 500 - 650 kg/m³
Partition Coefficient (log Kow): Not determined
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not considered reactive under normal temperatures and pressures
Conditions to Avoid: Strong heat sources; exposure to moisture for extended periods; storage with incompatible materials
Incompatible Materials: Strong oxidizing agents, strong acids, alkalis
Hazardous Decomposition Products: Trimethylamine, hydrogen chloride, nitrogen oxides, carbon monoxide may form on thermal decomposition
Hazardous Polymerization: Will not occur
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat): 3,425 mg/kg; considered low toxicity
Skin Corrosion/Irritation: May cause mild irritation on prolonged contact
Serious Eye Damage/Irritation: May cause moderate irritation
Respiratory Sensitization: Not classified as a respiratory sensitizer
Skin Sensitization: No evidence of skin sensitization reported
Carcinogenicity: No information showing choline chloride as a carcinogen
Reproductive Toxicity: Not suspected to impair fertility or harm unborn children at normal exposure levels
Chronic Effects: No known long-term effects with proper handling
Eco-Toxicity: Low risk for aquatic and terrestrial environments; not classified as hazardous to aquatic life
Persistence and Degradability: Expected to rapidly degrade and not persist in the environment
Bioaccumulative Potential: Not expected to accumulate in living organisms
Mobility in Soil: High water solubility suggests choline chloride may be mobile in soil, likely subject to natural attenuation processes
Other Adverse Effects: Not expected to contribute to ozone depletion, global warming, or other significant environmental impacts under normal use
Waste Treatment Methods: Dispose of product in accordance with local, state, and federal regulations; product may be suitable for landfill after consultation with authorities
Packaging Disposal: Containers should be thoroughly emptied and then recycled or disposed of according to regulations
Special Disposal Precautions: Avoid releasing large amounts into the environment; do not flush into sewers, surface water, or groundwater
UN Number: Not regulated as dangerous according to UN recommendations
UN Proper Shipping Name: Choline Chloride
Transport Hazard Class: Not hazardous
Packing Group: Not assigned
Environmental Hazards: Not dangerous to the environment during transport
Special Precautions for Transport: Prevent moisture ingress and container damage during transport; secure loads to avoid movement and spillage
Transport Labeling: No special labeling requirements under normal transport conditions
Safety, Health, and Environmental Regulations Specific for the Substance: Compliant with EU REACH registration; listed in TSCA inventory in the United States; covered under WHMIS in Canada without special classification
Labeling Requirements: Not subject to mandatory hazard labeling under GHS for most uses
Other Regulation Details: Handle in accordance with local occupational safety and health guidelines; feed and food use regulated by relevant authorities such as FDA (US) and EFSA (EU)
Restrictions: Some restrictions may apply depending on use (e.g., pharmaceutical, food additive applications)
