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Name: Cholic Acid Chemical Formula: C24H40O5 Synonyms: 3α,7α,12α-Trihydroxy-5β-cholanic acid Appearance: White crystalline powder Odor: Odorless Uses: Used in scientific research, pharmaceutical applications, and studies involving bile acid metabolism Common Sources: Extracted from bovine bile or produced synthetically for laboratory use CAS Number: 81-25-4
Classification: Not considered hazardous under GHS; still, any chemical can pose risks when handled improperly Health Risks: Prolonged skin or eye contact can cause irritation; ingesting large amounts may affect the liver or digestive system Symbols: Avoid direct exposure, as repeated handling without protection could lead to discomfort or sensitization over time Warning: Dust can irritate airways if inhaled in significant quantities inside enclosed areas
Active Ingredient: Cholic Acid at high purity (more than 98% in research-grade material) Common Impurities: Others bile acids like deoxycholic acid, trace solvents from manufacturing processes Form: Pure substance as single chemical entity, with no major inactive excipients present in most research samples
Eye Contact: Rinse gently with running water for fifteen minutes; removing contact lenses if present eases cleaning Skin Contact: Wash affected area with soap and water; watch for any delayed redness or rash Inhalation: Move to fresh air, help the person breathe deeply, and seek attention if cough or dizziness lasts Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice if any symptoms appear General Advice: Provide medical guidance for persistent discomfort, especially for allergic responses or large exposures
Suitable Extinguishing Media: Use dry chemical, CO2, foam, or water spray Unusual Hazards: Combustion produces carbon monoxide, carbon dioxide, and possibly irritating fumes Protective Equipment: Wear full protective clothing and self-contained breathing apparatus during large fires Additional Recommendations: Move containers from fire area if possible, avoid inhaling smoke or decomposition products
Personal Protection: Wear gloves, eye protection, dust mask or respirator for larger spills Spill Cleanup: Sweep up carefully to avoid dust formation, place in closed, labeled container for disposal Environmental Precautions: Prevent runoff to drains or natural waterways Ventilation: Keep area ventilated; use HEPA-filter vacuums or damp cleaning methods for fine particles
Handling: Avoid breathing dust, minimize skin or eye contact, work under fume hood or with good room circulation Storage Conditions: Store in dry, cool, and well-ventilated location, away from strong oxidizers Container Materials: Use tightly sealed glass or plastic bottles to prevent contamination and moisture absorption
Engineering Controls: Laboratory fume hoods, good general ventilation, local exhaust as needed Personal Protective Equipment: Chemical-resistant gloves, lab coat, and safety goggles as basic defense Respiratory Protection: Dust mask or respirator for procedures generating airborne particles Hygiene Measures: Wash hands thoroughly after handling; never eat, drink, or smoke in areas where cholic acid is used
Molecular Weight: 408.6 g/mol Boiling Point: Decomposes before boiling Melting Point: About 198-203°C Solubility: Poorly soluble in cold water, better in alcohol and organic solvents Stability: Stable under normal lab conditions, moisture can cause caking or minor degradation Appearance: As white, odorless crystalline powder
Chemical Stability: Remains stable under typical storage, breaks down in strong acids, bases, or oxidizers Reactivity Hazards: Contact with oxidizing agents could produce hazardous byproducts or cause exothermic reactions Condition to Avoid: High heat, open flames, direct light for prolonged periods, contact with strong oxidizing chemicals Hazardous Decomposition: Fumes of carbon oxides, possible toxic gases if exposed to open fire or intense heat
Routes of Exposure: Ingestion, skin, eye, and inhalation Acute Effects: High-dose ingestion could disturb digestion or liver function; dust may cause coughing or throat irritation Chronic Effects: Long-term laboratory exposures not widely studied, but repeated skin contact may lead to dryness or increased sensitivity Allergies: Allergic reactions unlikely but possible for sensitive individuals; report new or unusual skin rashes
Aquatic Impact: Not highly toxic to aquatic life at working concentrations, but should not reach waterways in significant amounts Degradability: Breaks down slowly in soil and water through natural biological processes Environmental Persistence: Naturally occurring in animal systems, but accumulated waste needs proper management
Waste Handling: Transfer unused or spilled material to specified chemical waste bins approved for organic solids Disposal Method: Incinerate or send to licensed hazardous waste facility; dilute solutions poured down the drain may be illegal or harmful to treatment plants Container Disposal: Rinse containers well before disposal; follow institutional or local disposal protocols to avoid chemical leftovers
Shipping: Not classified as dangerous in most transport regulations, but keep in tightly closed packages to prevent leakage and contamination Labeling: Mark containers with chemical identity and hazard warnings as set by workplace safety codes Precautions: Separate from food and incompatible chemicals; avoid loading with oxidizers or corrosives
Workplace Safety: Subject to general laboratory safety, chemical hygiene, and hazard communication rules Global Regulations: Not restricted under major international transport or safety conventions, but national or state/local rules may apply Waste Laws: Disposal falls under hazardous chemical waste depending on local environmental protection standards
