© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: Chloroform
Chemical Name: Trichloromethane
CAS Number: 67-66-3
Manufacturer: Refer to supplier or distributor information
Recommended Use: Laboratory reagent, solvent, chemical synthesis
Emergency Contact: Refer to local emergency response numbers or poison control center
GHS Classification: Carcinogenicity (Category 2), Acute Toxicity Oral (Category 4), Skin Irritation (Category 2), Eye Irritation (Category 2A), Specific Target Organ Toxicity: Single Exposure (Category 3)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, suspected of causing cancer, causes skin and eye irritation, may cause drowsiness or dizziness
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated area, wear protective gloves and eye protection, wash thoroughly after handling, store locked up
Chemical: Chloroform
Chemical Formula: CHCl3
Concentration: ≥99%
Impurities: Contains trace stabilizer (e.g., 1% ethanol) in certain preparations
Synonyms: Trichloromethane, Methane trichloride
Inhalation: Move person to fresh air, keep at rest, seek medical advice if symptoms persist
Skin Contact: Immediately remove contaminated clothing, wash skin with plenty of soap and water, seek medical attention for any signs of irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get medical advice
Ingestion: Do not induce vomiting, rinse mouth, never give anything by mouth to an unconscious person, seek immediate medical attention
Symptoms: Dizziness, headache, lethargy, nausea, respiratory distress, potential liver and kidney effects with large exposure
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical powder, CO2, or water spray
Specific Hazards: Produces phosgene, hydrogen chloride, and carbon monoxide on thermal decomposition
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Firefighting Guidelines: Stay upwind, prevent runoff from entering water sources, cool containers exposed to flames with water spray
Special Measures: Avoid breathing fumes, containers may explode in heat
Personal Precautions: Evacuate area, ensure adequate ventilation, eliminate ignition sources, avoid inhalation and skin contact
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not allow to enter drains or watercourses
Cleanup Methods: Absorb with inert material (sand, vermiculite), collect in suitable containers for disposal, ventilate the area thoroughly, wash spill site after removal
Disposal Advice: Dispose of in accordance with local, regional, national, and international regulations
Handling: Work in a well-ventilated area, avoid exposure to heat, sparks, or open flames, use appropriate personal protection, minimize vapor release, avoid prolonged or repeated exposure
Storage Conditions: Store in tightly closed containers, keep away from incompatible materials such as strong bases, oxidizers, and alkali metals, store in cool, dry, well-ventilated locations away from direct sunlight and sources of ignition
Special Considerations: Use safety cabinets for flammable or volatile organics, keep containers securely labeled and upright, limit access to trained personnel
Occupational Exposure Limits: OSHA PEL: 50 ppm (TWA), NIOSH REL: 2 ppm (ceiling)
Engineering Controls: Use chemical fume hood, process enclosures, local exhaust ventilation
Personal Protection: Wear chemical-resistant gloves (e.g., nitrile), safety goggles, lab coat, and use respiratory protection if ventilation is inadequate
Hygiene Measures: Wash hands after handling, do not eat or drink while using chemical, keep contaminated clothing off work area
Monitoring: Conduct regular air monitoring, ensure emergency showers and eyewash stations are available
Appearance: Clear, colorless, volatile liquid
Odor: Sweet, ether-like
Boiling Point: 61°C (142°F)
Melting Point: -64°C (-83°F)
Flash Point: None (nonflammable)
Vapor Pressure: 213 hPa at 20°C
Vapor Density: 4.12 (air = 1)
Specific Gravity: 1.48 at 20°C
Solubility: Slightly soluble in water, soluble in ethanol, ether, acetone
Other: Evaporates easily, dense vapor can travel along ground and collect in low areas
Chemical Stability: Stable under normal handling and storage conditions
Conditions to Avoid: Heat, flames, sparks, incompatible materials
Incompatible Materials: Strong bases, alkali metals, reactive metals, strong oxidizers
Hazardous Decomposition: Phosgene, hydrogen chloride, chlorine, carbon monoxide, carbon dioxide
Polymerization: Will not occur in typical environments
Acute Toxicity: Harmful if swallowed or inhaled, may cause CNS depression, respiratory irritation
Chronic Effects: Prolonged exposure linked to cancer (IARC Group 2B), liver and kidney toxicity
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Symptoms of Exposure: Dizziness, headache, nausea, fatigue, respiratory difficulty, unconsciousness at high doses
Carcinogenicity: Classified as possible human carcinogen
Sensitization: Not reported as a skin sensitizer
Environmental Fate: Volatile, partially persistent in air and groundwater, evaporates readily into atmosphere
Toxicity to Aquatic Life: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Mobility in Soil: Low to moderate, contaminated groundwater risk
Bioaccumulation: Low potential, though can persist in environment
Degradation: Some photodegradation in air, slow in water and soil without sunlight
Disposal Methods: Dispose through licensed hazardous waste contractor, incineration preferred if possible with appropriate scrubbers
Packaging Disposal: Triple rinse containers, remove labels, follow hazardous chemical container disposal laws
Special Precautions: Do not dispose to sewer, environment, or regular solid waste stream, consult local environmental regulations
Contaminated Product: Treat as hazardous waste
UN Number: UN 1888
UN Proper Shipping Name: Chloroform
Hazard Class: 6.1 (Toxic substance)
Packing Group: III
Hazard Labels: Toxic (skull and crossbones), may require additional information for marine transport
Special Transport Requirements: Keep container tightly closed, transport in secure, upright position, ensure appropriate documentation and emergency response guides travel with shipment
OSHA: Regulated under Hazard Communication Standard
TSCA: Listed in Toxic Substances Control Act Inventory
SARA: Section 302, 313 listed, subject to emergency planning and release reporting
RCRA: Classified as hazardous waste
EPA: Clean Air Act Hazardous Air Pollutant, subject to Superfund reporting for releases
International Regulations: Covered under WHMIS (Canada), REACH (EU), Australian WHS, and other national inventories
Label Elements: Requires GHS pictograms and hazard statements on packaging
