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Product Name: Carbonate-Bicarbonate Buffer Capsules
Manufacturer: Refer to supplier’s information sheet for current manufacturer contact
Product Use: Laboratory reagent for pH buffering
Synonyms: Sodium carbonate-sodium bicarbonate buffer capsules
Contact Address: Manufacturer address available on request
Phone Number (for emergencies): Refer to emergency supplier contacts
Date Prepared: Most recent revision date supplied by manufacturer
Physical State: Solid
GHS Classification: Eye Irritant (Category 2A), Skin Irritant (Category 3)
Signal Word: Warning
Hazard Statement: Causes serious eye irritation, may cause skin irritation, can be harmful if swallowed
Pictograms: Exclamation Mark
Precautionary Statement: Avoid contact with eyes and skin, avoid inhaling dust, wash hands thoroughly after handling
Routes of Exposure: Eye contact, skin contact, ingestion, inhalation
Other Hazards: Dust may cause respiratory tract irritation
Sodium Carbonate (Na2CO3): 30–70% by weight, CAS No. 497-19-8
Sodium Bicarbonate (NaHCO3): 30–70% by weight, CAS No. 144-55-8
Inactive Fillers: Trace amounts (food-grade cellulose or silica, if present)
Possible Additives: Magnesium stearate as lubricant in low concentrations
Impurities: Levels below safety thresholds; refer to supplier analysis
Eye Contact: Rinse cautiously with water for 15–20 minutes, remove contact lenses, get medical attention if irritation persists
Skin Contact: Rinse affected area with soap and water, remove contaminated clothing, seek medical help if irritation develops
Inhalation: Move person to fresh air, provide oxygen if breathing is difficult, consult physician for persistent symptoms
Ingestion: Rinse mouth thoroughly, do not induce vomiting, contact poison control or physician immediately
Note for Medical Personnel: Treat symptomatically, monitor electrolyte balance if large amount ingested
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, or foam
Special Hazards: Product does not readily burn, thermal decomposition may produce carbon dioxide and sodium oxide fumes
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective clothing
Advice for Firefighters: Move containers from fire area if safe to do so, prevent runoff from entering drains
Explosion Data: Not prone to explosion under normal fire conditions
Personal Precautions: Wear protective gloves, goggles, dust mask; avoid creating dusty conditions
Environmental Precautions: Avoid discharge to drains or surface waters, contain spill to prevent environmental contamination
Methods for Cleanup: Sweep up material, place in suitable closed container, ventilate area, wash residues with water
Large Spill Response: Use industrial vacuum for cleanup, prevent powder from becoming airborne
Disposal: See Section 13 for waste management
Handling: Handle in a well-ventilated space, avoid breathing dust, use appropriate personal protective equipment, keep container tightly closed
Storage Conditions: Store at room temperature, keep dry, protect from direct sunlight, avoid extreme moisture, segregate from acids
Incompatible Materials: Strong acids, aluminum, ammonium compounds
Hygiene Measures: Wash thoroughly after handling, do not eat or drink while handling
Storage Class: General chemical, separate from food products
Engineering Controls: Use local exhaust ventilation or process enclosure to minimize dust
Personal Protection:
Gloves: Chemical-resistant disposable or nitrile
Eye Protection: Safety goggles or face shield
Respiratory: Dust mask or respirator for large spills or poorly ventilated areas
Clothing: Lab coat or apron to prevent skin contact
Occupational Exposure Limits:
Sodium carbonate: OSHA PEL not established; consider nuisance dust limit (15 mg/m³ total dust)
Sodium bicarbonate: Similar nuisance dust limits apply
Other Precautions: Eyewash and safety showers recommended in work area
Appearance: White crystalline powder/capsule
Odor: Odorless
Odor Threshold: Not applicable
pH (1% solution): 9.2 – 10.8
Melting Point/Freezing Point: Sodium carbonate: 851°C decomposes; sodium bicarbonate decomposes above 50°C
Boiling Point: Not applicable, decomposes before boiling
Solubility in Water: Fully soluble
Vapor Pressure: Not applicable
Relative Density: About 2.2 (water = 1)
Partition Coefficient (n-octanol/water): Not applicable
Flash Point: Not flammable
Evaporation Rate: Not applicable
Decomposition Temperature: Sodium bicarbonate: Above 50°C liberates CO₂
Viscosity: Not applicable in solid form
Chemical Stability: Stable under normal laboratory and storage conditions
Conditions to Avoid: Excessive heat, moisture, contact with acids, strong oxidizers
Materials to Avoid: Acids (produces CO₂ gas), ammonium salts, aluminum metal
Hazardous Decomposition Products: Carbon dioxide, sodium oxide upon thermal decomposition
Possibility of Hazardous Reactions: Rapid CO₂ gas generation with acids; avoid confined spaces
Acute Toxicity: Sodium carbonate oral LD50 (rat): 2800 mg/kg; sodium bicarbonate oral LD50 (rat): 4220 mg/kg
Skin Irritation: Prolonged contact can cause mild irritation or redness
Eye Irritation: Causes irritation and possible redness or watering
Inhalation: Dust may irritate respiratory tract, coughing, sneezing
Chronic Effects: Prolonged exposure can cause dermatitis or eye damage
Sensitization: Not expected to cause allergic response
Carcinogenicity: Not classified as carcinogenic
Mutagenicity: No evidence of mutagenic properties
Reproductive Toxicity: No known reproductive hazards
Medical Conditions Aggravated by Exposure: Pre-existing eye, skin, respiratory disorders
Ecotoxicity: Low-level toxicity to aquatic life due to pH shift
Persistence and Degradability: Easily dissociates to ions, does not persist
Bioaccumulation potential: Not expected
Mobility in Soil: High mobility; can leach readily due to solubility
Aquatic Impact: Can disturb local water chemistry if released in significant quantities
Environmental Precautions: Avoid bulk discharge to waterways
Other Adverse Effects: No lasting ecosystem impact when used as directed
Waste Disposal Method: Dispose of contents/container to hazardous or approved chemical waste facility in accordance with local, regional, and national regulations
Safe Disposal Practices: Dissolve in excess water, neutralize acids before flushing, do not release substantial quantities to drains, follow municipal requirements
Packaging Disposal: Triple-rinse container, puncture or crush before landfilling or recycling if permissible
Contaminated Packaging: Must be disposed of as hazardous waste
UN Number: Not regulated as a hazardous material
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Proper Shipping Name: Non-hazardous for ground, sea, and air transport
Environmental Hazards: Not an environmental hazard under standard transport regulations
Special Precautions: Secure packagings to prevent rupture and release of dust
Transportation Labeling: General chemical, no special DOT label required
OSHA Status: Not considered hazardous under OSHA Hazard Communication Standard
TSCA Listing: Ingredients appear on the TSCA inventory
EU Classification: Regulated under REACH and CLP as an irritant
DSL/NDSL (Canada): Components listed
SARA Title III: Not reportable under Sections 302, 304, 313
California Proposition 65: No components listed
Other Regulation: Adhere to any local workplace safety standards regarding chemical storage and handling
