© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: Phosphate Buffered Saline (PBS)
Chemical Family: Inorganic salt solution
Product Use: Laboratory buffer, cell culture
Manufacturer: Please refer to product packaging
Contact Information: Refer to supplier details on the label or accompanying documents
Synonyms: PBS Buffer, Dulbecco’s PBS
CAS Number: Mixture (Sodium chloride 7647-14-5, Potassium chloride 7447-40-7, Disodium phosphate 7558-79-4, Monopotassium phosphate 7778-77-0)
Emergency Contact: Refer to local emergency numbers and supplier emergency line
GHS Classification: Not classified as hazardous according to GHS
Label Elements: No pictogram required
Signal Word: None
Hazard Statements: Solution does not present a hazard under normal conditions of use
Precautionary Statements: Avoid prolonged skin and eye contact, practice good laboratory hygiene
Potential Health Effects: May cause mild eye or skin irritation for sensitive individuals
NFPA Ratings: Health: 1, Flammability: 0, Reactivity: 0
Sodium Chloride: 137 mM (CAS 7647-14-5)
Potassium Chloride: 2.7 mM (CAS 7447-40-7)
Disodium Phosphate (Na2HPO4): 8 mM (CAS 7558-79-4)
Monopotassium Phosphate (KH2PO4): 1.5 mM (CAS 7778-77-0)
Water: To 100% volume (CAS 7732-18-5)
Other Ingredients: None
Impurities: No reportable impurities
Eye Contact: Rinse immediately with plenty of water for several minutes, lift eyelids for thorough rinsing, seek medical attention for persistent irritation
Skin Contact: Wash area with soap and water, remove contaminated clothing, consult a physician if symptoms develop
Inhalation: Move exposed individual to fresh air, seek medical assistance if symptoms appear
Ingestion: Rinse mouth with water, drink water to dilute, medical attention recommended for large volumes or persistent discomfort
Most Important Symptoms: Mild irritation, dryness, or redness in sensitive tissues
Advice for Physicians: Treat symptomatically, no specific antidote
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: None known for this aqueous solution
Hazards from Combustion: Solution itself will not combust; container may melt or rupture in a fire
Protective Equipment: Firefighters should use standard protective gear, including self-contained breathing apparatus
Firefighting Instructions: Move containers away from fire area if safe, use water spray to keep containers cool, manage run-off to avoid environmental contamination
Specific Hazards: Possible liberation of small quantities of toxic fumes if boiled to dryness and heated to decomposition
Personal Precautions: Wear appropriate gloves and eye protection, use laboratory coat
Environmental Precautions: Prevent large releases from entering drains or waterways
Methods for Cleaning Up: Absorb with inert material such as paper towels, collect into container for disposal, wash spill area with water
Decontamination Procedures: Clean surfaces with soap and water
Reporting: Inform laboratory supervisor or safety office if required by local protocol
Handling: Handle in accordance with good laboratory practice, use caution to avoid spills and splashes, avoid ingestion and inhalation
Storage Conditions: Store at room temperature or as directed by manufacturer (2–30°C), keep container tightly closed, protect from contamination
Incompatible Materials: Avoid strong acids, strong bases, and oxidizing agents
Special Handling Requirements: Use only in designated laboratory areas, label containers clearly
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke in use areas
Occupational Exposure Limits: No established limits for ingredients at concentrations present
Engineering Controls: Use general or local exhaust ventilation if significant volumes handled
Personal Protective Equipment: Wear safety glasses with side shields, laboratory gloves (nitrile or latex), and protective clothing
Respiratory Protection: Not required for normal use; respiratory protection may be required for aerosolized solutions in poorly ventilated areas
Environmental Exposure Controls: Minimize release to environment, use spill trays where possible
Appearance: Clear, colourless liquid
Odour: Odourless
pH: 7.2–7.6 at 25°C
Boiling Point: About 100°C
Melting Point/Freezing Point: 0°C
Flash Point: Not applicable
Solubility: Fully miscible with water
Vapour Pressure: Similar to water
Relative Density: Approximately 1 g/mL
Partition Coefficient: Not applicable
Viscosity: Like water
Evaporation Rate: Similar to water
Chemical Stability: Stable under normal laboratory and storage conditions
Possibility of Hazardous Reactions: Not known to react dangerously with other materials in standard laboratory practice
Conditions to Avoid: Excessive heat, freezing, contamination
Incompatible Materials: Strong acids, strong bases, oxidizers
Hazardous Decomposition Products: May generate small quantities of irritating gases if evaporated completely and subjected to fire
Acute Toxicity: Ingredients in low concentrations present minimal toxicity; ingestion of large amounts may cause electrolyte imbalance
Skin Corrosion/Irritation: May produce mild irritation on prolonged or repeated exposure
Eye Damage/Irritation: May cause mild eye irritation
Respiratory Sensitization: Not expected to cause sensitization
Carcinogenicity: Not listed by IARC, NTP, OSHA as a carcinogen
Reproductive Toxicity: Not expected at low concentrations
Chronic Effects: No known effects from standard laboratory exposure
Symptoms: Mild skin/eye irritation, minor gastrointestinal upset if ingested in large amounts
Ecotoxicity: Ingredients at use concentrations do not pose a significant hazard to aquatic or terrestrial organisms
Persistence and Degradability: Components will readily dissolve and dilute in water, naturally present mineral ions
Bioaccumulative Potential: Low, as ingredients are not known to bioaccumulate
Mobility in Soil: Highly mobile in aqueous environments
Other Adverse Effects: Excessive discharge may disrupt local water chemistry due to shifts in saline balance
Waste Treatment Methods: Dispose in accordance with local, regional, and national regulations
Unused Solution: Small volumes may be poured down the drain with copious water, following approval from safety officer
Contaminated Packaging: Triple rinse bottles before recycling or disposal, dispose similarly to laboratory plastics
Precautions: Prevent unauthorized access to large volumes, avoid disposal into surface waters
Special Considerations: Refer to institutional policies for any biological contamination
UN Number: None assigned
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated as dangerous goods
Packing Group: Not applicable
Environmental Hazards: Not applicable
Transport in Bulk: Not regulated
Special Precautions: Keep container upright, secure during transport
US Regulations: Not subject to reporting under SARA Title III or CERCLA, not listed under TSCA as a hazardous substance
EU Regulations: Not classified under REACH; no mandatory labeling under CLP/GHS
International Inventories: Components appear on the major chemical inventories
Other Regulatory Information: No known regulatory restrictions for laboratory or medical use at typical concentrations
Labelling Requirements: Follow institutional policies and national laboratory standards
