© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Chemical Name: Bromotrimethylsilane
Synonyms: Trimethylsilyl bromide
CAS Number: 2857-97-8
Typical Use: This compound comes up in a lot of research labs, where it helps in protecting groups during synthesis or assists breaking down certain molecules in organic chemistry. Its purpose can crop up whenever there’s a need to generate silyl ethers or modify functional groups efficiently. Folks working with this chemical usually sit around an academic bench or maybe a pharmaceutical process pilot plant.
GHS Classification: Flammable liquid, acute toxicity (oral and inhalation), skin corrosion/irritation, eye damage
Hazard Statements: Flammable and reacts violently with water. Skin and eyes pay the price if contact happens: burns, irritation, tearing. Vapors irritate the respiratory system. If someone breathes it in, or gets it on their skin for longer than a blink, it’s a medical issue.
Pictograms: Flammable, corrosive, acute toxicity
Chemical Identity: Bromotrimethylsilane, purity usually over 95% in commercial and research supply.
Impurities: Depending on the process, minor silyl halides or organosilicon traces.
Inhalation: Get the person out of the space with fumes right away; breathing difficulty or throat irritation means getting fresh air and quick medical attention. Oxygen in serious cases.
Skin Contact: Remove contaminated clothes immediately, rinse skin with running water for several minutes, don’t delay—seek emergency help if irritation sticks around.
Eye Contact: Rinse eyes gently with water for at least 15 minutes, making sure eyelids stay apart. Medical help comes before anything else.
Ingestion: Don’t encourage vomiting. Rinse mouth well. Go for immediate care, especially if the person feels sick or drowsy.
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, or alcohol-resistant foam work best. Water never mixes well—risk of explosive reaction.
Special Hazards: Fire releases toxic gases like hydrogen bromide, silicon oxides, methyl bromide, which can cause breathing trouble.
Protective Equipment: Full protective gear, positive-pressure self-contained breathing equipment.
Personal Precautions: Everyone clears out who does not need to be there. Open the space for air flow if you can without putting yourself at risk. Full protective clothing with goggles, gloves, and a face shield keeps skin and eyes covered.
Environmental Precautions: Prevent chemical from reaching drains, water sources, or soil. This material turns dangerous on contact with water.
Clean-up Methods: Absorb spill with dry, inert materials—vermiculate or sand. Gather in sealed chemical waste containers, avoid water at all costs.
Handling: Use only in well-ventilated places or fume hoods, no open flames or heat sources nearby. Containers need strong seals, and keep all possible contact to a minimum. Don’t eat, drink, or smoke where the chemical lives.
Storage: Store away from water, alcohols, acids, and oxidizers. Dry, cool, well-ventilated storage helps stop vapor buildup. Bottles need tight closure and non-metallic seals since Bromotrimethylsilane can chew through certain metals.
Engineering Controls: Fume hoods, chemical-resistant countertops, and local exhaust aim to yank vapors away from breathing zones.
Personal Protective Equipment: Nitrile or neoprene gloves, full goggles, and lab coats come standard. Face shields if splash likely. Respirators required if ventilation falls short.
Hygiene Measures: Wash hands well after use, even if gloves went on. Keep contaminated workwear away from living spaces.
Appearance: Colorless to pale yellow liquid
Odor: Pungent, almost like acetic acid but harsher and chemical.
Melting Point: Around -60°C
Boiling Point: Close to 103°C
Flash Point: 10°C
Solubility: Reacts with water, dissolves in organic solvents such as ether or benzene.
Vapor Pressure: Notable at room temperature, meaning it can fill a poorly ventilated room with irritating fumes.
Density: About 1.33 g/cm³
pH: Not applicable, reacts before you can measure it in water.
Chemical Stability: Stays stable in dry, closed containers below room temperature. Breaches in storage let moisture react and create pressure.
Incompatible Materials: Water, acids, alcohols, strong oxidizers. Any contact means heat, fumes, sometimes violent release.
Hazardous Decomposition Products: Hydrogen bromide, trimethylsilanol, silicon oxides. All require careful venting since inhaling these byproducts makes matters worse.
Inhalation Hazards: Breathing vapors irritates the lungs fast, causing cough, sore throat, even pulmonary edema if exposure runs high.
Skin Hazards: Causes burns, redness, blisters. Serious injuries if left untreated.
Eye Hazards: Vapors or liquid splash brings tearing, pain, possible vision damage.
Ingestion Hazards: Mouth and throat burns, nausea, vomiting, in some cases, internal injury.
Chronic Effects: No strong evidence on chronic exposure, but high concentration or repeated contact increases sensitivity and the chance of lasting skin or lung issues.
Environment Fate: Bromotrimethylsilane hydrolyzes in water into trimethylsilanol and hydrogen bromide, both toxic to aquatic life.
Persistence and Degradability: Once released, breaks down quickly, but the byproducts harm water bodies.
Bioaccumulation: Not considered bioaccumulative, but spills create long-term effects—a reminder on why drains and waterways must stay protected.
Toxicity to Aquatic Organisms: Fish and invertebrates do not tolerate spills, so strict controls help the ecosystems nearby chemical workspaces.
Waste Disposal Methods: All leftover Bromotrimethylsilane and contaminated gear should head to a hazardous waste facility. Incineration in a chemical waste burner under controlled conditions works best.
Contaminated Packaging: Must be disposed by specialty handlers—just rinsing and tossing in the landfill leads to releases down the line.
Legal Compliance: Stick with national and local hazardous waste rules, since this chemical brings down steep fines and environmental scrutiny if handled carelessly.
UN Number: UN 1993 (for flammable liquid, dangerous chemical)
Transport Hazard Class: 3 (Flammable Liquids), secondary for corrosives
Packing Group: II
Special Transport Notes: Needs robust secondary containment, clear hazard labeling, and full documentation to meet regulations. Spills in transit not only cause regulatory headaches but often mean specialized emergency teams risk exposure.
Global Chemicals Inventory: Listed in several regions as a hazardous chemical. It attracts attention under workplace safety laws in the US, Europe, and Asia.
Reporting Requirements: Storage above certain volumes demands reporting to local safety authorities. Permits for storage and disposal checklists keep handlers on track.
Worker Protection: Training for safe handling ranks high under employer duty, including routine PPE checks and emergency drills. Regular audits and safety reviews create a living compliance routine instead of a stack of forms hidden in a binder.
