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MSDS for Bromothymol Blue

Identification

Product Name: Bromothymol Blue
Chemical Formula: C27H28Br2O5S
Synonyms: BTB, 3,3’-dibromothymolsulfonphthalein
CAS Number: 76-59-5
Recommended Use: Laboratory reagent, pH indicator
Supplier/Manufacturer: Listed on product label
Emergency Contact: Local poison control center or one provided by manufacturer

Hazard Identification

GHS Classification: Not classified as a hazardous material by GHS standards for pure chemical
Hazard Statements: May cause mild skin and eye irritation; not acutely toxic
Pictograms: No standardized pictogram required
Precautionary Statements: Avoid contact with skin and eyes, avoid inhaling dust, wash hands after handling
Signal Word: None required

Composition / Information on Ingredients

Chemical Name: Bromothymol Blue
Concentration: >99% (analytical grade)
Impurities: Not expected to contain significant impurities
Additives: None reported in pure substance form

First Aid Measures

Inhalation: Move to fresh air, seek medical attention for any breathing difficulty
Skin Contact: Wash with soap and water, remove contaminated clothing, consult medical help if irritation persists
Eye Contact: Rinse cautiously with water for several minutes and remove contact lenses if present
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice if feeling unwell

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide for small fires
Hazardous Combustion Products: Carbon oxides, sulfur oxides, hydrogen bromide, toxic fumes may form
Recommended Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus
Unusual Fire Hazards: Fine dust dispersed in air may ignite, product appears stable under normal handling

Accidental Release Measures

Personal Precautions: Avoid inhalation and contact with skin, provide adequate ventilation
Protective Equipment: Wear chemical-resistant gloves, safety goggles, and lab coat
Emergency Procedures: Contain and collect spillage with damp cloth or vacuum with HEPA filter
Environmental Precautions: Do not allow product to enter drains or watercourses

Handling and Storage

Safe Handling: Minimize dust, avoid breathing powders, use only in fume hood or well-ventilated area, wash thoroughly after use
Storage Conditions: Store in tightly closed container, keep in dry, cool, well-ventilated place, protect from light and moisture
Incompatible Materials: Strong oxidizing agents, strong acids and bases

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific exposure limits assigned
Engineering Controls: Use local exhaust ventilation or work in fume hood
Personal Protective Equipment: Chemical safety goggles, appropriate gloves, lab coat or apron, if risk of high exposure consider using NIOSH-approved respirator
Hygiene Measures: Do not eat, drink, or smoke while handling chemicals, wash hands before breaks and at end of workday

Physical and Chemical Properties

Appearance: Dark green to blue powder or crystals
Odor: Odorless
Odor Threshold: Not available
pH: 6.0 (yellow) to 7.6 (blue) in aqueous solution, changes with pH range
Melting Point: Decomposes above 204°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Slightly soluble in water, more soluble in alcohols and alkalies
Flash Point: Not flammable
Vapor Pressure: Not applicable/very low
Density: ~1.46 g/cm³
Partition Coefficient: Not available
Decomposition Temperature: >204°C

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: High heat, light exposure, extreme moisture, strong acids or bases
Incompatible Materials: Strong oxidizers, acids, and bases
Hazardous Decomposition Products: May release fumes of bromine, sulfur oxides, or carbon oxides when heated to decomposition
Polymerization: Will not occur under normal conditions

Toxicological Information

Acute Toxicity: Low oral and dermal toxicity in laboratory animals based on available data
Skin Contact: May cause slight irritation
Eye Contact: May cause mild, transient irritation
Ingestion: Expected to be non-toxic at low doses; large amounts can cause irritation and discomfort
Inhalation: Dust may cause irritation of respiratory tract
Chronic Effects: Not known to cause long-term adverse health effects
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity/Teratogenicity: No reliable studies showing mutagenic, reproductive, or developmental hazards

Ecological Information

Ecotoxicity: No reliable quantitative data on aquatic toxicity; not expected to cause significant ecological harm in laboratory quantities
Persistence and Degradability: Not expected to degrade quickly; halogenated aromatic structures tend to persist
Bioaccumulative Potential: Low based on molecular properties, insufficient measured data
Mobility in Soil: Not readily mobile due to low water solubility
Other Effects: Avoid release to environment as part of best practices

Disposal Considerations

Waste Treatment Methods: Dispose according to local, regional, or national regulations
Chemical Waste Disposal: Gather in closable, labelled containers; pass for incineration or chemical waste treatment at licensed facility
Contaminated Packaging: Treat empty containers as hazardous; rinse thoroughly before recycling or disposal
Environmental Precautions: Prevent large quantities from reaching sewage, drainage systems, or natural waters

Transport Information

UN Number: Not regulated
DOT/IATA/IMDG: Not classified as dangerous for transport
Special Precautions: Ship in sealed container, avoid release of dust in transit

Regulatory Information

OSHA Status: Not considered hazardous under OSHA Hazard Communication Standard
TSCA Status: Listed in TSCA inventory
SARA Title III: Not a reportable substance
WHMIS Classification (Canada): Not controlled
REACH (EU): Registered, not subject to authorization or restriction
Labeling Requirements: Labelling as non-hazardous in most jurisdictions; local rules may require GHS compliant label
Other Regulations: Subject to state, local, or institutional safety requirements for safe chemical management