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Material Safety Data Sheet — Bromocresol Purple

Identification

Product Name: Bromocresol Purple
Synonyms: 5',5''-Dibromo-o-cresolsulfonphthalein; BCP
Chemical Formula: C21H16Br2O5S
CAS Number: 115-40-2
Molecular Weight: 540.23 g/mol
Supplier: Chemical and laboratory suppliers in most global markets
Recommended Use: Laboratory reagent, pH indicator in analytical chemistry
Restrictions: Avoid use in food, drug, or household products

Hazard Identification

Classification: Not classified as hazardous under GHS criteria, but care required in handling laboratory chemicals
Signal Word: None required under typical classification
Pictograms: None under standard hazard communication; treat as laboratory chemical
Hazard Statements: May cause mild irritation to skin, eyes, and respiratory tract; avoid generating dust or breathing dust
Precautionary Statements: Use personal protective equipment, wash thoroughly after handling, work in ventilated area
Symptoms of Exposure: Irritation of eyes or respiratory tract, slight redness or discomfort on skin contact

Composition / Information on Ingredients

Chemical: Bromocresol Purple
CAS Number: 115-40-2
Concentration: 98–100%
Impurities: Trace inorganic salts, organic dye-related impurities below 2%
Other Additives: None intentionally added; formulation is single constituent material

First Aid Measures

Inhalation: Move person to fresh air, seek medical help if symptoms develop or persist.
Skin Contact: Wash skin thoroughly with soap and water; remove contaminated clothing.
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if easy to do.
Ingestion: Rinse mouth out, give water to drink; seek medical attention for any symptoms.
Delayed Effects: Not anticipated in most laboratory exposures; monitor for ongoing irritation.
Notes for Physicians: Treat symptomatically, no specific antidote indicated.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or foam for surrounding fire.
Specific Hazards: Product may emit toxic fumes of bromine, sulfur oxides, and carbon oxides on combustion.
Protective Equipment: Full firefighting turnout gear, self-contained breathing apparatus recommended.
Firefighting Advice: Avoid inhaling smoke, control runoff water, isolate from strong oxidizers.

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, laboratory coat; avoid dust formation; ventilate area.
Environmental Precautions: Prevent entry to drains, sewers, and water sources.
Clean-up Procedures: Sweep up carefully, avoid raising dust, place in suitable container for disposal.
Decontamination: Wash area with water and detergent, ventilate space thoroughly after cleanup.
Waste Disposal: Dispose as hazardous laboratory waste in accordance with local regulations.

Handling and Storage

Precautions for Safe Handling: Handle in well-ventilated area; minimize dust generation; use appropriate personal protection.
Storage Conditions: Store in tightly closed containers in cool, dry, well-ventilated location; protect from light and moisture.
Incompatibilities: Avoid strong oxidizing agents and acids.
Safe Transfer: Use dedicated tools and containers to prevent cross-contamination.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established exposure limit for Bromocresol Purple.
Engineering Controls: Use fume hood or local exhaust where dust or aerosol may form.
Personal Protection: Safety glasses with side shields, nitrile or latex gloves, laboratory coat, dust mask in case of powder use.
Respiratory Protection: NIOSH-approved particulate respirator for handling quantities generating dust.
Hygiene Measures: Wash hands before eating, drinking, or smoking; avoid skin or eye contact.

Physical and Chemical Properties

Appearance: Violet to brownish powder or crystalline solid
Odor: Odorless
pH: Acidic solution pH ~5.2 (yellow), basic pH >6.8 (purple, color transition range 5.2-6.8)
Melting Point: 240–245°C (decomposes)
Boiling Point: Not available (decomposes before boiling)
Solubility: Slightly soluble in water, readily soluble in alcohol and alkaline solutions
Vapor Pressure: Not applicable (non-volatile solid)
Density: ~1.5 g/cm³
Partition Coefficient: Not available
Stability: Stable in normal laboratory conditions, avoid high heat, strong oxidants

Stability and Reactivity

Reactivity: Stable under ordinary conditions.
Chemical Stability: Stable at room temperature in dry, sealed containers.
Hazardous Reactions: Reaction with strong oxidizing agents may cause fire or release toxic gases.
Hazardous Decomposition Products: Bromine, sulfur oxides, carbon oxides.
Incompatible Materials: Strong acids, oxidizers, reducing agents.
Polymerization: Not reported to occur.

Toxicological Information

Acute Toxicity: Data limited; no known acute toxicity in moderate laboratory exposures.
Chronic Effects: No clear chronic risk identified; avoid prolonged, repeated exposures.
Routes of Exposure: Inhalation, skin and eye contact, ingestion.
Symptoms: May cause mild skin/eye irritation or respiratory discomfort in dust form.
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA.
Mutagenicity/Reproductive Toxicity: No available data indicate genetic or reproductive hazards.

Ecological Information

Toxicity to Aquatic Life: No measured data, but as with laboratory dyes, avoid release into environment.
Persistence and Degradability: Not readily biodegradable; dye structure likely persists.
Bioaccumulation Potential: Not studied, but unlikely in common use quantities.
Environmental Precautions: Prevent chemical from entering waterways, soil, or drains.

Disposal Considerations

Waste Treatment: Collect chemical waste in designated containers; label for hazardous laboratory waste.
Disposal Methods: Hand over to licensed waste disposal contractor; incineration in controlled facility preferred.
Regulatory Requirements: Disposal must comply with local, state, and national regulations.
Decontamination: Clean secondary containers thoroughly before reuse or recycling; avoid environmental contamination.

Transport Information

UN Number: Not regulated for transport under ADR/RID, IMDG, IATA
Proper Shipping Name: Chemical, N.O.S. (laboratory chemicals)
Transport Hazard Class: Not classified as a hazardous good
Packing Group: None required
Special Precautions: Prevent spillage and breakage in transit, avoid exposure to moisture or strong sunlight.
Shipping Labelling: Not a dangerous good under most transport regulations.

Regulatory Information

GHS Status: Not classified as hazardous.
TSCA Listing: Listed on US Toxic Substances Control Act inventory.
EU REACH Status: Pre-registered
Other Inventories: Listed in Canada DSL, Australia AICS, Korea ECL, Japan ENCS
Workplace Labelling: Standard chemical hazard label; note potential irritant effects.
Specific Restrictions: Not intended for food, drug, or household use.