© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: Benzonase Nuclease (Recombinant 5KU)
CAS Number: 9025-65-4
Product Number: Specific to vendor, check packaging
Manufacturer: Refer to label or purchase documentation
Recommended Use: Laboratory research, nucleic acid hydrolysis
Contact Information: Includes emergency phone for supplier, address, email
Hazards: May cause respiratory irritation, skin sensitization with direct exposure, eye irritation possible from splashes
Globally Harmonized System (GHS): Not classified as hazardous under GHS for most applications, though dust generation during freeze-drying remains irritating
Pictograms: None typically required
Signal Word: None required for dilute working solutions, caution for concentrated or lyophilized protein
Hazard Statements: Prolonged inhalation or direct contact could lead to allergic reactions; protein material may sensitise skin
Precautionary Statements: Avoid breathing dust when handling powder form; wash skin thoroughly after use; use in a well-ventilated area
Active Ingredient: Benzonase Nuclease, recombinant endonuclease protein
Concentration: Typically supplied as 25-50 U/μl in buffered solution or lyophilized powder
Other Components: Stabilizers such as sodium chloride, Tris buffer, glycerol, trace preservatives
Impurities: Trace microbial proteins, none classified as hazardous
Form: Clear, colorless solution or white powder
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, consult physician if irritation persists
Skin Contact: Wash immediately with soap and water, remove any contaminated clothing, monitor for rash or irritation
Inhalation: Move affected person outside or to fresh air, encourage slow, deep breaths, seek medical attention if symptoms worsen
Ingestion: Rinse mouth with water, never induce vomiting, consult a physician if feeling unwell
Note to Medics: Treat topically as protein allergen; symptomatic management advised
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical powder, or CO2
Unsuitable Extinguishing Media: None identified for this material
Specific Hazards: Protein and excipients may decompose releasing nitrogen oxides or carbon oxides
Protective Equipment: Wear full protective gear including self-contained breathing apparatus
Hazard Combustion Products: Formation of typical protein decomposition gases which may be harmful if inhaled
Personal Precautions: Isolate spill; wear gloves, safety goggles, lab coat; prevent breathing dust
Environmental Precautions: Prevent release into drains or waterways; use appropriate absorbent material to trap liquid
Cleanup Methods: Collect powder with dampened cloth, absorb solution with inert material; dispose of in chemical waste containers; clean area with soap and water
Emergency Procedures: Notify responsible personnel of release, avoid creating aerosols
Precautions for Safe Handling: Avoid direct skin and eye contact, do not ingest, work in well-ventilated area, prevent aerosol formation
Safe Storage Conditions: Store in original container tightly closed; refrigerate (2-8°C) unless otherwise specified; protect from sunlight and freezing
Incompatible Materials: Strong oxidizers and acids possibly degrade protein
Storage Security: Limit access to trained users; ensure children or unauthorized workers do not have unmonitored access
Engineering Controls: Use local exhaust, lab fume hood, keep airborne levels to a minimum
Eye Protection: Safety glasses or splash goggles
Hand Protection: Nitrile or latex gloves, change gloves if contaminated
Skin Protection: Wear disposable lab coat or apron
Respiratory Protection: Use mask or respirator if powder created, N95 for routine handling
Hygiene Measures: Wash hands before breaks and at end of workshift; avoid eating, drinking, or smoking in work area
Appearance: Colorless to pale yellow solution, or white lyophilized powder
Odor: None noticeable
pH: Typically 7.0-8.5 in aqueous solution
Melting/Freezing Point: Not applicable for solution, powder stable up to 40°C
Solubility: Soluble in water and standard saline buffers
Boiling Point: Not applicable (decomposes on heating)
Vapor Pressure: Not applicable
Flash Point: Not determined
Density: Not measured, protein in aqueous solution
Viscosity: Comparable to water for solutions
Chemical Stability: Stable under recommended storage and usage conditions
Thermal Decomposition: Prolonged heat destroys activity, denatures active protein
Conditions to Avoid: Avoid extreme heat, repeated freeze-thaw cycles
Incompatible Materials: Strong acids, bases, and oxidizers
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides formed on burning
Polymerization: Does not occur
Acute Toxicity: No significant toxicity seen with exposure routes typical in lab settings
Chronic Effects: Prolonged or repeated contact can sensitize individuals; protein nature may trigger allergic reaction in sensitized people
Routes of Exposure: Eyes, skin, inhalation
Symptoms: Redness, itching, sneeze or respiratory discomfort in rare cases
Carcinogenicity: No evidence for protein-based material
Mutagenicity: Not expected
Other Effects: None known in non-sensitized humans
Ecotoxicity: No widespread environmental hazard; enzymatic degradation by natural microbes
Persistence and Degradability: Degraded quickly in soil and water due to protein structure
Bioaccumulation Potential: Little to none, protein does not persist
Mobility in Soil: Protein binds quickly to organic matter and is degraded
Other Adverse Effects: None anticipated under normal laboratory disposal
Waste Disposal: Dispose unused product via licensed waste management contractor; treat as biological waste from research setting
Contaminated Packaging: Rinse bottles/test tubes then dispose in biohazard or appropriate chemical waste stream
Special Precautions: Prevent direct release into sewage, soil, or surface water
Legal Requirements: Follow local, regional, and institutional guidelines for chemical and biological waste
UN Number: Not regulated for transport under most conditions
Proper Shipping Name: Non-hazardous protein reagent
Transport Hazard Class: Not classified as hazardous
Packing Group: Not assigned
Environmental Hazards: None for small quantities as typically shipped
Special Precautions: Keep cold with gel packs if refrigerated; avoid physical damage, ensure upright position
Labelling Requirements: Not regulated as hazardous substance in most regions
International Inventories: Check compliance with US (TSCA), EU (EINECS/ELINCS), Canada (DSL/NDSL) as reagent product
Right-to-Know: Not listed on hazardous substance lists
Workplace Regulations: Use in compliance with OSHA, EU Directives, individual country occupational safety laws
Chemical Safety Assessment: Not required for enzyme proteins of this type supplied for research
