© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: ASCENTIS EXPRESS C18
Product Code: Various, including 53823-U, 53824-U
Manufacturer: MilliporeSigma (Sigma-Aldrich, Merck KGaA)
Supplier Address: 3050 Spruce Street, St. Louis, MO 63103, USA
Emergency Phone Number: 1-800-424-9300 (CHEMTREC)
Recommended Use: Chromatography, analytical lab use
Restrictions: For laboratory use only, not for drug, household, or food purposes
GHS Classification: Not classified as hazardous under GHS standards
Signal Word: None
Pictograms: None
Hazard Statements: No significant hazards identified with routine laboratory use under normal conditions
Precautionary Statements: Avoid inhaling dust, use only with adequate ventilation, prevent eye and skin contact
Routes of Exposure: Eye, skin, ingestion, inhalation
Acute Effects: May cause mild irritation to eyes, skin, and airways
Chronic Effects: No known chronic health effects with proper handling
Chemical Nature: Silica gel (solid, coated with octadecylsilyl derivatives)
Main Ingredients: Silica, surface-bonded C18 alkyl groups
CAS Number (Silica): 7631-86-9
Typical Purity: >95% silica by weight
Other Components: None required for disclosure
Impurities: Manufacturer states no hazardous impurities present above threshold
Inhalation: Move affected person to fresh air, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash area with soap and water, seek help for rash or irritation
Eye Contact: Rinse eyes thoroughly with water for at least 15 minutes, get medical attention if irritation continues
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice if large quantities are swallowed
Acute Symptoms: May cause mild irritation to eyes, skin, or airways
Suitable Extinguishing Media: Water spray, CO2, dry chemical, foam
Unsuitable Media: None known for this material
Hazards from Combustion: May release silicon oxides at high temperatures
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Other Instructions: Approach fire from upwind to avoid hazardous vapors
Personal Precautions: Avoid breathing dust, ensure good ventilation, wear suitable protective equipment
Environmental Precautions: Prevent entry into drains or waterways
Cleanup Methods: Carefully sweep up to avoid creating dust, collect in suitable containers for proper disposal
Decontamination: Wash spill area with water after material removal
Disposal: Dispose of following local environmental regulations
Precautions for Safe Handling: Avoid dust formation, use in well-ventilated area, wear proper protective gear
Incompatible Materials: Strong oxidizers, strong acids
Safe Storage Conditions: Store in tightly closed container, away from moisture and incompatible chemicals, room temperature
Specific End Use: Designed for laboratory analytical procedures, not for consumption
Other Handling Advice: Avoid contact with skin, eyes, and clothing
Occupational Exposure Limits: OSHA PEL (Silica - amorphous): 20 mppcf; ACGIH TLV: 10 mg/m³ (total dust); 3 mg/m³ (respirable dust)
Engineering Controls: Use fume hood or local exhaust to minimize airborne dust
Eye Protection: Safety glasses with side shields
Skin Protection: Lab coat, chemical-resistant gloves
Respiratory Protection: Use particle mask (N95) under dusty conditions or insufficient ventilation
General Hygiene: Wash hands after use, remove contaminated clothing and launder before reuse
Appearance: Solid, white to off-white powder
Odor: Odorless
pH: Not applicable (insoluble in water)
Melting Point/Freezing Point: >1700°C (silica component)
Boiling Point: Not applicable
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Not applicable
Solubility: Insoluble in water, organic solvents
Partition Coefficient (log Kow): Not available
Density: 0.4 – 0.7 g/cm³
Viscosity: Not applicable
Decomposition Temperature: >1600°C (silica)
Chemical Stability: Stable under normal lab conditions
Reactivity: Chemically inert with most substances
Conditions to Avoid: Generation of dust, strong acids, strong oxidizers
Hazardous Reactions: None known under normal use
Decomposition Products: May release silicon oxides at elevated temperatures
Polymerization: Will not occur
Acute Toxicity: Oral LD50 (rat): >5000 mg/kg (silica)
Skin Corrosion/Irritation: May cause mechanical skin irritation
Serious Eye Damage/Irritation: Can irritate eyes mechanically
Respiratory or Skin Sensitization: Not a known sensitizer
Mutagenicity: No data indicating mutagenic effects
Carcinogenicity: Amorphous silica is not classified as a human carcinogen; crystalline silica (quartz) is not present in dangerous amounts in this product
Reproductive Toxicity: Not expected
STOT-Se (Single Exposure): Inhalation of excessive dust may lead to coughing and upper respiratory discomfort
Aquatic Toxicity: Not expected to be toxic to aquatic life
Persistence and Degradability: Inorganic, not biodegradable, physically persists
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Immobile, remains in solid phase
Other Adverse Effects: No evidence of significant environmental hazard with proper disposal
Disposal Methods: Dispose of as non-hazardous laboratory waste, according to local, state, and federal regulations
Container Cleanup: Wash containers thoroughly before recycling or discarding
Reuse/Recycling: Recommend one-time use for analytical reliability
Special Precautions: Avoid dust when handling waste, prevent product entry into drains or waterways
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: None
Packing Group: None
Marine Pollutant: No
Special Precautions: Handle packaging to avoid dust release, ensure containers are tightly sealed during transport
TSCA Status: All components listed
SARA 313: Not subject to SARA Title III Section 313
California Proposition 65: Not listed as causing cancer or reproductive toxicity
REACH Registration: Exempt as an article
Labeling (US): Non-hazardous per OSHA 29 CFR 1910.1200
Other National Inventories: Listed in EU, Japan, Canada, and Australia chemical inventories
