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Product Name: Anhidrido Ftálico
Chemical Formula: C8H4O3
CAS No.: 85-44-9
Use: Production of alkyd resins, plasticizers, dyes, pharmaceuticals
Supplier: Obtain contact details from manufacturer or importer
Synonyms: Phthalic acid anhydride, 1,3-isobenzofurandione
GHS Classification: Acute toxicity (Category 4, inhalation), Skin irritation (Category 2), Eye irritation (Category 2A), Respiratory sensitization (Category 1), Skin sensitization (Category 1)
Signal Word: Danger
Hazard Statements: Harmful if inhaled, Causes skin and serious eye irritation, May cause an allergic skin reaction or respiratory irritation, Suspected of causing cancer (long-term exposure)
Pictograms: Exclamation mark, Health hazard
Potential Health Effects: Irritation to eyes, skin, upper respiratory tract; may trigger asthma or allergies; dust poses inhalation hazard even at low concentrations
Chemical Name: Phthalic Anhydride
CAS Number: 85-44-9
Concentration: ≥ 99%
Impurities: Traces of phthalic acid, maleic anhydride possible
Inhalation: Remove person from exposure area into fresh air; seek medical attention for difficulty breathing, symptoms of asthma, or persistent discomfort
Skin Contact: Remove contaminated clothes; immediately wash skin thoroughly with soap and water; contact healthcare provider if rash or persistent irritation develops
Eye Contact: Rinse cautiously with plenty of water for at least 15 minutes; remove contact lenses if present and easy; seek medical attention promptly
Ingestion: Rinse mouth; never give anything by mouth to an unconscious person; get medical advice if larger quantity is ingested or symptoms occur
Protection for First Responders: Use personal protective equipment, avoid dust exposure, and prevent self-contamination
Suitable Extinguishing Media: Use foam, dry chemical, carbon dioxide, or water spray (avoid high pressure streams that can scatter powder/dust)
Specific Hazards: Product can form explosive dust-air mixtures; may emit irritating fumes and phthalic acid under fire conditions
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective clothing
Firefighting Advice: Cool containers with water spray, prevent firefighting water runoff from contaminating environment
Personal Precautions: Evacuate area for large spills, ventilate space, avoid dust inhalation, wear suitable respiratory and skin protection.
Environmental Precautions: Prevent further leakage, keep away from drains, surface and ground waters, collect spilled material for proper disposal
Clean-Up Methods: Sweep or vacuum up (using explosion-proof tools), transfer to labeled containers; avoid dispersal of dust, wet wiping minimizes dust
Handling: Use only in well-ventilated areas, minimize dust generation, avoid all contact with skin, eyes, and clothing; employ local exhaust ventilation where dust occurs
Storage: Store in tightly closed containers, in a cool, dry, well-ventilated area, away from moisture, oxidizing agents, strong acids and bases; keep away from food and beverages
Specific Requirements: Ground containers to prevent static discharge, control dust ignition sources
Occupational Exposure Limits: OSHA PEL 1 ppm (6 mg/m³) TWA; ACGIH TLV 0.002 ppm (sensitizer)
Engineering Controls: Local exhaust, process enclosure, dust collection recommended
Personal Protection: Wear chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, flame-retardant protective clothing, suitable dust respirator or PAPR for levels above exposure limits
Hygiene: Wash hands and face before eating, drinking, or smoking; change soiled work clothes promptly
Appearance: White crystalline flakes or needles
Odor: Acrid, irritating
Odor Threshold: 0.003 ppm (can be detected at low concentration)
Molecular Weight: 148.12 g/mol
pH: Forms phthalic acid in contact with water (acidic)
Melting Point: 131°C
Boiling Point: 284°C (decomposes)
Flash Point: 152°C (closed cup)
Flammability: Combustible as dust or powder
Explosion Limits: Lower 1 g/m³ (dust); significant explosion risk as a fine powder
Vapor Pressure: 0.02 mmHg at 20°C
Solubility: Sparingly soluble in water, reacts to form phthalic acid; soluble in hot water, alcohol, ether
Auto-Ignition Temp: 580°C
Partition Coefficient (log Kow): 1.6
Chemical Stability: Stable under recommended storage conditions, decomposes in moisture to phthalic acid
Reactivity: Polymerizes slowly in the presence of water, incompatible with oxidizing agents, strong acids, alkalis, amines, and alcohols
Hazardous Decomposition Products: Carbon oxides, phthalic acid, irritating fumes
Conditions to Avoid: Heat, ignition sources, damp air, direct sunlight, and static discharge
Acute Toxicity: Oral LD50 (rat): 1530 mg/kg; Inhalation LC50 (rat): > 15 mg/L/1 hr
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Effects: Irritation to skin, eyes, respiratory tract, possible skin and respiratory sensitizer; repeated inhalation may trigger asthma-like effects
Chronic Exposure: Possible risk of long-term respiratory sensitization (occupational asthma); no conclusive evidence of carcinogenicity in humans
Additional Information: Persons with pre-existing allergies or asthma face increased risk of sensitization and severe effects
Ecotoxicity: Harmful to aquatic organisms; LC50 (fish, 96h): 3.5-12.2 mg/L (species-dependent)
Persistence and Degradability: Readily biodegradable in soil and water under aerobic conditions, hydrolyzed to phthalic acid
Bioaccumulation Potential: Low (log Kow 1.6)
Mobility in Soil: Moderate to high; leaching possible in presence of water
Other Adverse Effects: Avoid uncontrolled release to environment
Recommended Disposal Methods: Handle as hazardous waste—incinerate in an approved facility or landfill in accordance with local regulations; do not dispose into sewers, water bodies, or unlined landfill
Waste Codes: Use correct national or regional code for phthalic anhydride and contaminated packaging
Packaging Disposal: Rinse thoroughly, puncture before landfilling or send for recycling if possible
UN Number: 2214
Proper Shipping Name: PHTHALIC ANHYDRIDE
Hazard Class: 8 (corrosive), may also be labeled class 9 (miscellaneous, sensitizer)
Packing Group: II
Marine Pollutant: No
Special Transport Notes: Keep container sealed, upright, in cool area, away from incompatible loads; avoid spills—powder suppressants or sealed bulk packing preferred
OSHA: Regulated substance, listed in Hazard Communication Standard
EPA: TSCA listed, hazardous substance under CERCLA (reportable quantity 5,000 lbs), subject to SARA Title III reporting
EU REACH: Registered, substance of concern for respiratory sensitization
Other: International regulations may require special labeling for sensitizers; always check most recent country, regional, or local control lists
