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Product Name: Acetylacetone
Chemical Name: 2,4-Pentanedione
CAS Number: 123-54-6
Molecular Formula: C5H8O2
Synonyms: Pentane-2,4-dione; Diketone; Diacetylmethane
Recommended Use: Chemical synthesis, solvent, industrial applications
Manufacturer/Supplier: Supplier details depend on location and distributor
Contact Details for Emergency Issues: Refer to local Poison Control or emergency response number; general emergency contact for chemical orders
Classification: Flammable liquid (Category 3), Acute toxicity oral (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3)
Label Elements: GHS label includes flame, exclamation mark
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor; Harmful if swallowed; Causes skin irritation; Causes serious eye irritation; May cause respiratory irritation
Precautionary Statements: Keep away from sources of ignition; Do not breathe vapors; Avoid contact with skin and eyes; Use explosion-proof electrical equipment; Wear protective gloves and eye protection
Chemical Identity: Acetylacetone
Concentration: ≥99%
Impurities: Minor impurities may include small amounts of related diketones and water
CAS Number: 123-54-6
Molecular Weight: 100.12 g/mol
Other Components: None classified as hazardous under applicable regulations
Inhalation: Move person to fresh air; keep warm and at rest; seek medical advice if any symptoms develop such as headache, dizziness, cough, or shortness of breath
Skin Contact: Remove contaminated clothing immediately; rinse affected skin with plenty of water and soap; call a physician if irritation persists or develops
Eye Contact: Rinse cautiously with water for at least 15 minutes; lift eyelids occasionally; remove contact lenses if present and easy to do; seek medical help for sustained discomfort
Ingestion: Rinse mouth, do not induce vomiting; give water if person is conscious; seek immediate medical attention
Most Important Symptoms: Eye irritation, skin reddening, mild nausea, symptoms associated with central nervous system depression
Suitable Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry powder, water spray
Unsuitable Extinguishing Media: Strong water jet may spread the fire
Specific Hazards: Vapors are heavier than air and may travel along the ground; may form explosive mixtures with air; containers may rupture under fire conditions releasing vapors; thermal decomposition releases carbon oxides and toxic fumes
Protective Equipment: Full protective clothing and self-contained breathing apparatus for firefighters
Advice for Firefighters: Approach fire from upwind side; cool containers with water spray; avoid inhalation of combustion products
Personal Precautions: Evacuate unprotected personnel; eliminate all sources of ignition; ventilate area; wear impervious gloves, protective goggles, suitable protective clothing, and respiratory protection to reduce inhalation risk
Environmental Precautions: Prevent entry into sewers or groundwater; capture spills with inert absorbent (e.g., sand, earth, vermiculite)
Cleanup Methods: Collect spilled material mechanically, place in suitable waste container tightly sealed; clean contaminated area with plenty of water
Special Procedures: Isolate hazard area; notify local authorities if large spills occur; ensure cleanup supplies are readily available at points of use
Handling: Use away from heat sources, open flames, and sparks; ground and bond containers for transfer; avoid breathing vapors; wear proper protective equipment including gloves and goggles; use only in well-ventilated areas or with local exhaust
Storage: Store tightly closed in original container; keep in cool, dry, and well-ventilated area designated for flammable liquids; segregate from strong oxidizers and acids; keep container upright and secure against falling
Special Storage Considerations: Protect from sunlight and incompatible materials; store at temperature well below flash point; avoid storage near foods, beverages, or feed
Exposure Limits: No OSHA PEL or ACGIH TLV specifically set; use industrial hygiene practice to minimize exposure
Engineering Controls: Use chemical fume hood or local exhaust to limit vapor buildup; ensure emergency eyewash and safety shower are accessible
Personal Protective Equipment (PPE): Nitrile gloves recommended for hand protection; safety goggles for eyes; flame-resistant lab coat or apron for body; suitable respirator if ventilation is insufficient
Workplace Hygiene: Wash hands after handling; do not eat, drink, or smoke in work area; regularly inspect control equipment for leaks or failures
Appearance: Colorless to pale yellow liquid
Odor: Sweet, mint-like aroma
Melting Point: −23°C
Boiling Point: 140°C
Flash Point: 34°C (closed cup)
Evaporation Rate: Moderate (comparable to common ketones)
Flammability: Flammable liquid category 3
Vapor Pressure: 2.1 kPa at 20°C
Solubility: Miscible with most organic solvents; moderately soluble in water
Vapor Density: 3.5 (air = 1)
Density: 0.97 g/cm³ at 20°C
pH: Not applicable (neutral in solution)
Chemical Stability: Stable under normal handling and storage conditions; decomposes with strong oxidizers
Reactivity: May react vigorously with oxidizing agents, strong bases, and reducing agents
Conditions to Avoid: High temperatures, open flames, sparks, direct sunlight
Hazardous Decomposition: Carbon monoxide, carbon dioxide, and organic fumes from incomplete combustion or degradation
Polymerization: Not known to undergo hazardous exothermic polymerization under standard conditions
Acute Toxicity: Oral LD50 (rat): 875 mg/kg; inhalation and dermal toxicity data indicate moderate hazard
Skin Irritation: Causes inflammation, redness, or dermatitis after prolonged contact
Eye Irritation: Serious eye irritation demonstrated in laboratory animal studies
Respiratory Effects: Vapors can cause cough, sore throat, dizziness, or drowsiness; possible central nervous system depression at high exposures
Chronic Effects: Liver and kidney effects observed in prolonged or repeated exposure in animal models
Other Health Effects: Not classified as carcinogenic based on current data; not associated with genetic or reproductive toxicity under occupational settings
Acute Aquatic Toxicity: Harmful to aquatic life with short-term exposure; fish LC50 (96h) ~100 mg/L (species dependent)
Chronic Aquatic Toxicity: Limited data; not expected to cause long-term ecological harm at low concentrations
Persistence and Degradability: Readily biodegradable in standard environmental tests
Bioaccumulation: Low potential based on octanol-water partition coefficient (log Kow ~0.4)
Mobility in Soil: Expected to have high mobility through soil due to water solubility
Other Effects: Avoid disposal or release to open water systems to prevent ecosystem contamination
Waste Treatment: Collect as hazardous waste; do not pour into drains or environment
Disposal Methods: Use certified chemical waste disposal contractor; incineration under controlled conditions preferred
Unusable Product or Residue: Minimize residue, triple rinse containers, include rinsate in waste batch
Container Disposal: Decontaminated containers may be recycled or disposed as permitted by local regulation
UN Number: 2310
Proper Shipping Name: Acetylacetone
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Marine Pollutant: Not classified as a marine pollutant
Special Precautions: Secure tightly; avoid all heat and ignition sources during transport; check with carrier for additional restrictions or requirements
OSHA: Classified as hazardous under Hazard Communication Standard
TSCA Inventory: Listed
REACH Registration: Registered substance in the EU
IARC Carcinogenicity: Not classified
SARA Title III: Not subject to reporting under SARA Sections 302, 304, or 313
Other Local/International Regulations: Subject to workplace and transportation labeling in accordance with national and international rules; check jurisdiction-specific requirements for occupational and environmental health standards
