Chemists first came across acetonitrile during efforts to refine coal tar long before chromatography shaped laboratory life. Early uses were simple: solvent extraction, reaction media, small-scale syntheses. By the 1970s and 80s, high performance liquid chromatography (HPLC) shifted the focus to clarity, purity, and repeatability. It’s hard to imagine modern analysis before the introduction of gradient-grade solvents, a leap that let researchers run more complex separations. What really pushed this solvent ahead was the discovery that its polarity, low ultraviolet (UV) absorbance, and chemical stability matched up perfectly with the fast-moving world of HPLC. The standards went up over time. Manufacturers adapted to meet the strictest demands for trace impurities, creating a new level of solvent purity just for analytical work. The backstory isn’t about one brilliant discovery; it’s about small advances in chemical separation and a steady drive for sharper, more reliable data.
Acetonitrile in HPLC gradient grade isn’t just a cleaner version of its industrial relative. This solvent must jump through hoops set by instrument makers and international organizations. It must avoid baseline noise, drag as little water as possible, and dodge every possible UV-absorbing contaminant. Analytical scientists depend on consistency between lots, so each batch undergoes tight scrutiny. Many labs go through thousands of liters every year for pharmaceutical quality control, food safety, and soil or groundwater analysis. It’s a workhorse, but every bottle holds up to years of regulation, scrutiny, and user complaints. Most users I’ve talked to describe a small sense of relief cracking open a new bottle, knowing this batch passed so many invisible tests along the way. For students and seasoned analysts alike, access to a reliable solvent can mean the difference between repeatable answers and a week spent chasing ghosts in the data.
Water-clear and easy flowing, acetonitrile keeps its cool even at refrigerator temperatures. Its boiling point, much lower than water, suits fast evaporation in both preparative and analytical contexts. The near-neutral polarity lets it dissolve an impressive spread of molecules, making it a core ingredient in reverse-phase HPLC separations. Its low viscosity allows for rapid travels through fine columns, reducing pressure and extending instrument lifetimes. It resists oxidation, photolysis, and hydrolysis under typical lab conditions, so it keeps its edge across storage seasons. UV absorption is the big story: proper acetonitrile doesn’t cloud readings at wavelengths used by most HPLC detectors. Variability in UV transparency can push an entire data set sideways, so purity checks are routine before a new batch hits the shelves.
HPLC gradient grade stands as a hard-won achievement for those who remember headaches caused by “just-pure-enough” solvents of the past. Liquid chromatography demands clarity at the single-digit parts per billion (ppb) for some contaminants. Labels often list water content, UV absorbance at key wavelengths, color, and residue after evaporation. Some suppliers provide batch-by-batch chromatograms, so customers judge the baseline with their own eyes. This level of detail isn’t meant to impress but to guarantee the solvent won’t upset careful separation. Exact specs may vary between brands but always circle back to low water, low non-volatile residue, and razor-thin UV cut-off at relevant wavelengths. It took pressure from frustrated chromatographers to reach this standard.
Most commercial sources rely on distilling crude acetonitrile under inert gas, sometimes several times, then passing the product through polishing cartridges such as activated alumina or molecular sieves. Some outfits use freeze-pump-thaw cycles to strip leftover gases. Manufacturers keep the details close, but the general outline is always careful distillation, closely monitored water removal, and minimal exposure to atmospheric contaminants. Final polishing steps sometimes separate one brand from the next. Nobody in the field overlooks the long quest to cut UV-absorbing trace impurities, where even a small slip in drying or storage can undo weeks of careful processing.
Chemists often push acetonitrile to its limits as both participant and solvent. In pure form, its cyano group makes it versatile for nucleophilic substitutions and organometallic reactions. Researchers have built whole catalogues of reactions based on its behavior as an aprotic, polar phase. Alkylation, condensation, and transition-metal catalysis all draw on its inertness and stability at laboratory scales. Derivatizations involving acid or base sometimes rely on its strong solvent power, while synthetic manipulations of the molecule itself expand into pharmaceutical or materials chemistry. Still, in analytical laboratories, purity matters more than chemical adventure, making modifications rare once the bottle arrives.
Acetonitrile turns up under the trade names methyl cyanide and ethanenitrile. Across research libraries, those two are the names you’ll most often see. Standard chemical indexing calls it MeCN. Product lines highlight “HPLC,” “Gradient,” or “Ultra Pure” on the label. Synonyms mainly serve chemists trying to cross-reference procedures from older literature. No matter the title, everyone refers back to the transparent, colorless solvent that underpins a huge slice of modern analysis.
A bottle of acetonitrile on the bench carries more responsibility than many realize. Breathing its vapors too long leads to headaches, while skin or eye contact demands proper cleanup. Unlike some older solvents, it’s not especially prone to spontaneous explosions or peroxides, but it burns fiercely if spilled near an open flame. Modern regulations spell out storage away from ignition sources, along with constant attention to personal protective equipment, fume hoods, and strict labeling. Frequent refresher training becomes less a box to check than a daily necessity, especially for lab newcomers. Emergencies move beyond slips and spills—long-term exposure can chip away at health, so institutions keep a close watch on air quality and proper waste disposal.
The reach of HPLC gradient grade acetonitrile extends far past chemistry departments. Pharmaceutical companies test the ingredients in life-saving drugs with it, tracking every step from raw materials to dissolved pills. Environmental labs search for pesticides and industrial residues in drinking water, counting on clean baselines to draw accurate conclusions. Forensic scientists sort out blood, tissue, and evidence samples years after a crime, thanks largely to the solvent’s consistent performance. Clinical researchers rely on it for high-throughput analysis that keeps diagnostic results flowing each hour. I’ve met food researchers who run hundreds of samples per day—pesticides, allergens, antibiotics—all relying on this single solvent. Small imperfections in solvent purity can force entire recalls, so the demand for guaranteed quality never slows.
A constant push for higher sensitivity in analytics feeds continuous work on solvent purity. Some labs examine trace impurities at levels unimaginable a decade ago, using advanced mass spectrometry and spectroscopic tools. Quality checks now include not only established methods like Karl Fischer titration for water, but also advanced chromatography and residual solvent analysis. Instrument suppliers and solvent makers work in near-lockstep, as new detectors and columns often ask for even cleaner solvents. Industry groups look into greener synthesis and alternatives, driven by a need to balance performance with environmental cost. As a longtime analyst, I’ve watched these improvements cancel out noise, shrink detection limits, and open fields that no one expected to advance so quickly just from upgrading a solvent. The link between solvent progress and real-world insight never seems to weaken.
Toxicologists view acetonitrile with a clear sense of caution. Short exposures don’t always leave a mark, but accidents or large releases bring genuine health risks. On entering the body, acetonitrile metabolizes down to hydrogen cyanide—a fact that’s given it a tough reputation in regulatory circles. Chronic inhalation or skin absorption can trigger nervous system symptoms; long-term studies track liver, lung, and kidney effects. Regulatory bodies keep workplace exposure limits low, measured with frequent air monitoring and biological samples. I’ve been in labs where a misplaced vent or poorly fitted waste container set off alarms and emergency drills. Most safety frameworks treat it with the same care as far stronger toxins, a smart move considering its subtle danger profile.
Acetonitrile’s role in analytics may get challenged as sustainability pressure grows. Manufacturing—still tied to acrylonitrile production as a by-product—raises questions about petrochemical reliance and supply risk. Market shortages in the last two decades drove up prices and highlighted the need for more stable, sustainable sourcing. Research into biodegradable, less toxic solvents heats up every year, with teams searching for “green” alternatives that match the old standard. Meanwhile, analytics teams worldwide rely on improvements in purification and packaging that squeeze out one last drop of unreadable impurity. I see academic and industrial labs rethinking waste streams, recycling methods, and energy use during manufacture. As HPLC continues tightening performance and speed requirements, the pressure only builds for solvents—acetonitrile included—to keep up, adapt, and defend their place in labs already searching for cleaner, safer, more sustainable futures.
If you ever step into a research lab, you might catch sight of clear bottles labeled “Acetonitrile HPLC Gradient Grade.” It turns out that this isn’t just some fancy chemical tucked away for show. Acetonitrile of this purity serves a real and crucial role. High-Performance Liquid Chromatography (HPLC) wouldn’t be reliable without it, especially in labs chasing accurate results for food safety, pharmaceutical development, and environmental monitoring.
Every scientist knows that small contaminants in solvents can wreck data. Regular acetonitrile might bring in trace metals or organic leftovers, which actually show up in measurements or clog up expensive columns. That’s where the gradient grade difference becomes clear. Manufacturers test and filter it to make sure impurities stay at levels so low they won’t mess with the machine’s sensitive detectors. Experiments become easier to trust when the baseline runs flat and clean, instead of jumping all over the chart.
Say a company wants to check whether their crops carry residues of pesticides. Strict rules keep harmful chemicals out of our food, so labs hunt for molecules at tiny concentrations—sometimes a few parts per billion. Acetonitrile makes that possible. It dissolves lots of chemicals and flows smoothly with water, letting researchers separate and spot the smallest traces. That matter of trust in results means people eat safer food and drink cleaner water.
Drug companies run HPLC tests at nearly every stage, starting with drug discovery and running through manufacturing. By mixing acetonitrile with water and using it as a ‘mobile phase,’ researchers spot differences between active compounds and impurities with pinpoint accuracy. I’ve watched analysts light up when they solve a contamination mystery or clear a new drug for human trials. Every time, the reliability of the test allows for better medicine, fewer side effects, and a smoother path from idea to pharmacy shelf.
Labs can go through a lot of solvent fast. On a busy day, an HPLC system might use several liters. Some labs recycle used acetonitrile using careful distillation, both to cut costs and lower the impact on the environment. By switching methods, reducing waste, and handling solvents with care, safety pros and green advocates work together to reduce chemical footprint.
Everyone dealing with acetonitrile faces snags: tight global supply, price spikes, or safety issues. This solvent is flammable, and it’s toxic if not handled right. Training helps, along with well-maintained fume hoods and strict inventory controls. Some labs try greener alternatives where they can, but most analytical protocols still rely on the unbeatable mix of purity, consistency, and chemical compatibility that high-grade acetonitrile brings to the table.
People rarely hear about something like “HPLC gradient grade acetonitrile,” but every clean water sample, safe apple in the lunchbox, or tablet at the pharmacy owes a little debt to the stuff. For lab workers, solid science starts with trust in a single bottle. For everyone else, it quietly makes the world a bit safer.
Acetonitrile acts as a linchpin for labs all over the world. Anyone tracking down analytes with high-performance liquid chromatography knows acetonitrile makes or breaks a separation. When moving onto mass spectrometry for detection, the purity of the solvent impacts everything from signal intensity to instrument longevity. HPLC gradient grade acetonitrile sits in the middle ground on the purity spectrum—cleaner than industrial grades, but not quite hitting the ultra-pure bar set by LC-MS specific variants.
Manufacturers often guarantee HPLC gradient grade acetonitrile with less than 0.0001% water and specified limits for UV-absorbing impurities. Many labs reach for it due to solid reliability and cost savings, especially for routine separations. The trouble starts when the detector switches from UV to MS. Mass spectrometers latch onto impurities invisible by UV but loud in the mass spectra. That means every ghost peak, adduct, or ion suppression can trace back to the bottle of solvent on your bench.
Actual results show that some sources of HPLC gradient grade acetonitrile work fine for robust analytes at low detection levels. It comes down to the load your application throws at the system. If you’re scrutinizing trace-level compounds or running discovery work demanding lowest background and highest sensitivity, cutting corners on solvent purity risks more headache than it saves in budget.
Acetonitrile intended for gradient HPLC rarely causes catastrophic instrument failure, but hidden contaminants build up over time. In my years assisting LC-MS users troubleshoot, the most stubborn background noise usually came down to compromised solvent purity. You lose critical ions, see tailing, or chase phantom peaks all day. The data stops telling the truth. Corporate quality sheets only reveal so much; actual performance swings between suppliers, with many bottles behaving differently across manufacturing dates.
Call it penny wise, pound foolish. Using “just HPLC grade” for LC-MS turns into wasted runs, more blanks, and frustrated lab staff. Once, a client downstreamed clinical samples. Each run with cheaper acetonitrile brought up a recurring mass at m/z 82 and 102, both traced to plasticizer residue—undetectable by HPLC UV, but flagging in MS. Ever since, I point every lab to test every new lot with a full blank run. Your time goes further than a few saved dollars per liter.
Labs running dozens of samples daily feel real cost pressure. Switching to the highest-spec LC-MS acetonitrile seems excessive at first glance. Yet, the real calculation lies in downtime. An LC-MS system doesn’t just chew through acetonitrile. It multiplies issues if the background grows too noisy. You don’t spot trace contaminants with your eyes, only in lost sensitivity or unexpected ions. The risk grows for regulated settings where every sample counts.
Some suppliers do deliver HPLC grade acetonitrile that’s genuinely close to LC-MS specs. Relationships matter. Ask for detailed impurity analysis, test new batches with stripped-down blank runs, and monitor signal noise regularly. Investing in higher purity starts seeming practical once you factor in troubleshooting time, reruns, and lost samples. No substitute exists for hands-on verification of suitability—especially when one batch from the same vendor runs clean, but the next puts your chromatography in the weeds.
No lab supply catalogue tells the whole story. Every researcher chasing low detection needs a healthy skepticism toward labels on solvent bottles. Before trusting HPLC gradient grade acetonitrile in your LC-MS, stress test with your application. For high-stakes or trace work, higher-purity variants justify themselves in the results. Balancing cost and data quality pays off by keeping your science believable—and your mass spec happier in the long run.
Acetonitrile pulls its weight in many labs, especially those running high-performance liquid chromatography. Anyone who has spent time around this solvent knows the dangers it brings. Keeping people safe and research reliable starts with respecting what even the cleanest grade can do if mishandled. Acetonitrile isn’t just flammable. Even the vapor can cause headaches, dizziness, and, over time, nerve and organ damage. If you ever got a whiff of it escaping the bottle, you probably remember the sharp, penetrating smell and may have felt your eyes sting. It really gets your attention.
Safe storage begins with a solid container system. Polyethylene and glass cause fewer problems, but metal, unless specifically rated for acetonitrile, can react and rust. Flammable chemical cabinets rated for solvents belong in every lab that uses this compound. These cabinets should stay far away from electrical switchboards, hot water tanks, open flames, and direct sun. Temperature swings make it more volatile, and nobody wants extra pressure building up inside bottles.
Acetonitrile demands good labeling. Every time I walk into a crowded storage room, I look for clear hazard markers: clear statements about flammability, chemical name, and a date of receipt. People sometimes forget to rotate stock, but old acetonitrile breaks down and can fuel peroxide formation. Shelf life matters, especially in work that counts on exact purity.
Don’t skimp on ventilation. Storing a few liters in a fume hood or, better yet, a dedicated flammable chemical vault with active ventilation can really stop vapor buildup. That’s a lesson learned after a friend’s lab filled with an untraceable stench until air exchange improved.
Anyone planning to pour or pipette acetonitrile should gear up. Long sleeves, chemical-resistant gloves—nitrile or neoprene—plus goggles and, ideally, a face shield, have helped me avoid the bite from a splash. This solvent cuts right through cheap gloves and attacks exposed skin within seconds. It’s also good to avoid latex gloves, which offer little protection.
Folks often skip the fume hood for quick transfers, but every squirt of vapor raises health risks. I worked with a team that always used mechanical pipettors and clamp stands for larger bottles. Hands stay off cap threads, spills disappear, and the solvent evaporates fast enough that there’s almost no trace left behind if you wipe it up right away. Those habits reduce everyone’s long-term exposure by a wide margin.
Waste is another big concern. Dumping it down the drain isn’t just illegal; it wrecks wastewater systems and endangers the community. Designated non-chlorinated solvent drums should always stand close to the work area to encourage safe and consistent habits. I’ve seen a few labs disciplined for ignoring this, and nobody enjoys a stern visit from the safety office.
Regular safety drills and refreshers go a long way. I’ve seen even seasoned researchers slip up without reminders. Training sessions on acetonitrile hazards and emergency procedures make a real difference—especially when everyone gets familiar with spill kits and proper ventilation settings.
Monitors for volatile organics do more than just satisfy audit checklists. Placing them in storage and prep areas helps spot leaks early before they turn costly. Choosing smaller bottles if possible, and only opening the amount used in a few days, also limits exposure.
The bottom line is simple: safe chemistry rests on habits, not luck. Acetonitrile earns respect in the lab with every bottle that arrives, and following storage and handling precautions keeps it from turning dangerous in an instant.
Acetonitrile has become a go-to solvent in high-performance liquid chromatography (HPLC), particularly for gradient elution. Folks in the lab trust it because of its low viscosity and strong eluting power. If you’re running samples and you want clarity in your results, the grade you pour into your instrument makes a world of difference. In my own experience working in an analytical lab, struggling with noisy baselines or sudden ghost peaks usually led right back to using inferior solvents. You waste time troubleshooting issues that have nothing to do with the method but everything to do with your starting materials.
Acetonitrile labeled as HPLC Gradient Grade must meet tight specifications. The assay, which tells you how much of your bottle is pure acetonitrile, comes in at no less than 99.9%. The water content rarely creeps above 0.05%, typically determined by Karl Fischer titration—every chemist’s friend for moisture checks. Other solvents in this category, used in critical quantitative work, match these numbers. They don’t skimp because impurities sneak up on you, clouding baselines and hiding compounds you actually want to detect.
UV absorbance sets another important threshold. For acetonitrile at HPLC Gradient Grade, absorbance should remain low across key wavelengths. At 254 nm, absorbance must not exceed 0.005 absorbance units (AU). At 265 nm and 365 nm, upper limits are 0.003 AU and 0.01 AU, respectively. If your solvent fails here, your chromatogram risks extra noise or background, and that’s money and time down the drain.
Nobody enjoys repeating a run because some unknown impurity chimed in. Factory workers producing this solvent sweat the details so analysts see what they expect—just target peaks, not background static. Low residue levels matter, too. Non-volatile matter (what’s left behind after evaporation) should stick below 1 milligram per liter. If you’re lucky enough to work in a lab with regular QA checks, you learn that even a slightly off bottle messes with detection limits for sensitive analytes.
Heavy metal contamination can ruin detector performance and even the column. For acetonitrile, limits for trace metals—iron, copper, nickel—sit tightly at under 0.1 parts per million. It might look like overkill, until a single run gums up a detector or produces puzzling retention shifts. It happened on one of my shifts, and those are lessons you don’t forget.
Labs can’t just trust the label. Reputable suppliers back their product with batch certificates and spectral data. Smart teams invest in periodic in-house checks. If something seems off in retention, or if broad baseline drifts start popping up, swapping to a fresh bottle of validated acetonitrile often solves it. It costs more upfront, but you save hours in troubleshooting.
Timeouts between runs call for tightly capped containers and clean glassware—acetonitrile loves to pick up water from the air. Each shortcut weakens the reliability of results. HPLC has no mercy for shortcuts, and neither do customers or regulators.
Using acetonitrile that meets stringent purity standards turns out to be less about checking a box and more about building real trust in your results. Your baseline speaks for itself if you feed it clean, tested solvent that’s proven to meet today’s high demands for analytical rigor.
Scientists trust their solvents to keep experiments honest. Every chemist I know has reached for acetonitrile—a workhorse in analytical labs, especially in High-Performance Liquid Chromatography (HPLC). But ask around about what really goes into that bottle, and the answers can leave you spinning. Do gradient grade batches carry secret stabilizers? Any sneaky additives?
Acetonitrile for HPLC has one core job: let the analytes shine without muddy interference. Purity sits centerstage. Manufacturers strip out water, aldehydes, and anything that might trip up a sensitive detector. Most bottles labeled as “HPLC Gradient Grade” promise close to 99.9% purity. Quality control takes top billing—traces of UV-absorbing impurities, residual water, and metals get measured down to parts per billion. For those running gradient elution, any surprise compound in the solvent can cause ghost peaks and baseline drift, erasing hard-earned trust in a method.
Stabilizers and additives do have a place in the world of solvents, just not in every bottle. With certain solvents—like chloroform or peroxide-formers—manufacturers include small amounts of stabilizers to prevent dangerous breakdown or explosive byproducts. Acetonitrile doesn’t break down in typical storage. Its molecular backbone stays put under reasonable light and temperature. Most major suppliers, including Sigma-Aldrich, Fisher Scientific, and Merck, say outright: their HPLC gradient grade acetonitrile ships without added stabilizers or preservatives. My own experience, backed up by open conversations with supply reps and manufacturers, confirms this. Manufacturers expect users to want untainted solvent, one that won’t sneak in peaks or create extra background in the chromatogram.
No stabilizers mean fewer complications. Clean baselines, fewer troubleshooting headaches, and more reliable data. This works well for most users, since gradient HPLC often exposes the solvent to a wide range of detectors, each with its own quirky sensitivities. Additives might mean new, untested noise. But there is a flip side. Acetonitrile can pull atmospheric moisture or degrade if handled carelessly. Open a bottle too many times, and the purity can slip. Storage outside controlled environments can drag down performance faster than most realize. Sometimes, trace metals or dust from improper seals creep into the solution. These problems have nothing to do with stabilizers, they’re pure process slip-ups.
Working in a busy lab means solvents disappear fast. Still, investing in solvent safety caps limits air contact. Refrigeration—if practical—can slow down any unwanted changes. Testing an aliquot on a blank run catches impurities before real samples get wasted. Some groups order smaller bottles, cracking open only what can be used in a week. A little diligence here stretches the usefulness of every high-purity bottle, and safeguards results.
The best labs I know keep direct lines with their chemical suppliers. Every shipment comes with a certificate of analysis, providing a transparency trail. Don’t take vendors at their word; look for full specifications, even ask for chromatograms. Trust in solvent suppliers builds with consistency and openness. If anything in the bottle changes your data, raise the issue. Responsible manufacturers respond quickly—they know their reputation depends on it. Navigating solvent selection might sound mundane, but real science depends on these boring details lining up right.
| Names | |
| Preferred IUPAC name | ethanenitrile |
| Other names |
Methyl cyanide MeCN Ethanenitrile Cyanomethane Aceton |
| Pronunciation | /əˌsiː.təˈnaɪ.traɪl/ |
| Identifiers | |
| CAS Number | 75-05-8 |
| Beilstein Reference | 60260 |
| ChEBI | CHEBI:38457 |
| ChEMBL | CHEMBL1357 |
| ChemSpider | 5797 |
| DrugBank | DB03900 |
| ECHA InfoCard | 100.016.330 |
| EC Number | 607-001-00-5 |
| Gmelin Reference | 842 |
| KEGG | C00225 |
| MeSH | D002028 |
| PubChem CID | 6342 |
| RTECS number | AL7700000 |
| UNII | 019N35SW5V |
| UN number | UN1648 |
| Properties | |
| Chemical formula | CH3CN |
| Molar mass | 41.05 g/mol |
| Appearance | Clear, colorless liquid |
| Odor | Sweet, ether-like |
| Density | 0.786 g/cm³ |
| Solubility in water | Miscible |
| log P | -0.34 |
| Vapor pressure | 84 hPa (20 °C) |
| Acidity (pKa) | 25 (string) |
| Basicity (pKb) | pKb: 24.2 |
| Magnetic susceptibility (χ) | -8.2 × 10⁻⁶ |
| Refractive index (nD) | 1.344 |
| Viscosity | 0.37 mPa.s (20°C) |
| Dipole moment | 3.92 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 160.7 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | ΔfH⦵298 = +74.3 kJ·mol⁻¹ |
| Std enthalpy of combustion (ΔcH⦵298) | –1367 kJ·mol⁻¹ |
| Hazards | |
| GHS labelling | **"Danger: H225, H302, H312, H319, H332, P210, P261, P280, P305+P351+P338, P337+P313, P403+P233"** |
| Pictograms | GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | Hazard statements: H225, H302, H312, H319, H332, H412 |
| Precautionary statements | P210, P261, P273, P280, P301+P310, P303+P361+P353, P304+P340, P311, P312, P337+P313, P403+P233, P501 |
| NFPA 704 (fire diamond) | 2-3-0 |
| Flash point | 42 °C |
| Autoignition temperature | 525 °C |
| Explosive limits | 3.0 - 17% |
| Lethal dose or concentration | LD₅₀ Oral - Rat - 2,730 mg/kg |
| LD50 (median dose) | LD50 (oral, rat): 2730 mg/kg |
| NIOSH | Not Listed |
| PEL (Permissible) | 40 ppm |
| REL (Recommended) | 40 ppm |
| IDLH (Immediate danger) | IDHL: 500 ppm |
| Related compounds | |
| Related compounds |
Acetamide Acetic acid Acetone Acetaldehyde Acetonin |