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Product Name: Acetone
Chemical Formula: C3H6O
Synonyms: Dimethyl ketone, Propanone
CAS Number: 67-64-1
UN Number: UN1090
Recommended Use: Industrial solvent, laboratory chemical, cleaning agent
Supplier: Information provided by manufacturer or distributor, including emergency contact number.
Classification: Flammable liquids (Category 2), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3, narcotic effects)
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor. Causes serious eye irritation. May cause drowsiness or dizziness.
Pictograms: Flame, exclamation mark
Precautionary Statements: Keep away from heat, sparks, open flames. Avoid breathing vapors. Use explosion-proof equipment. Wash exposed skin after handling. Store in tightly closed container in cool, well-ventilated area.
Other Hazards: Repeated exposure may dry out or crack skin.
Chemical Name: Acetone
Concentration: ≥ 99%
CAS Number: 67-64-1
Impurities: May contain trace water or methanol, consult supplier certificate of analysis.
Inhalation: Remove affected person to fresh air. Support breathing as needed with oxygen or artificial respiration. Get medical attention if symptoms such as dizziness, headache, or nausea persist.
Skin Contact: Remove contaminated clothing. Rinse skin thoroughly with water. Seek medical advice if irritation continues.
Eye Contact: Rinse cautiously with water for several minutes, removing contact lenses if present and easy. Keep rinsing. Seek medical attention if irritation persists.
Ingestion: Rinse mouth. Do not induce vomiting. Call a poison center or health care provider directly. Provide medical professional with as much information as possible about the amount and time of ingestion.
Most Important Symptoms: Irritation, drowsiness, dizziness, headache, unconsciousness in severe exposures.
Suitable Extinguishing Media: Alcohol-resistant foam, dry powder, carbon dioxide.
Unsuitable Media: Water jets may spread the fire.
Specific Hazards: Vapor may form explosive mixture with air. Combustion produces carbon oxides, irritating fumes.
Protective Equipment: Wear full protective gear and self-contained breathing apparatus.
Firefighting Advice: Containers may explode in heat of fire. Cool with water spray from safe distance. Prevent runoff to sewers and waterways.
Personal Precautions: Isolate leak area. Ventilate location. Avoid breathing vapors. Use suitable personal protective equipment—chemical goggles, gloves, protective clothing.
Environmental Precautions: Prevent liquid from entering drains, soil, or surface water.
Spill Containment: Stop leak if safe. Contain spill with inert absorbent (sand, earth, vermiculite). Collect residues in appropriate containers. Clean contaminated area with plenty of water.
Reporting: Notify authorities if major spill causes environmental contamination.
Safe Handling: Use only in well-ventilated environments. Prevent static discharge by grounding containers and equipment. Avoid inhalation of fumes or contact with eyes and skin. No smoking or ignition sources. Use spark-proof tools.
Storage: Store in tightly closed, approved containers. Place in cool, dry, well-ventilated place. Keep away from direct sunlight, heat, oxidizers, acids, and bases. Separate from food and drink.
Incompatible Materials: Strong oxidizing agents, strong acids, halogens, alkali metals.
Hygiene Practices: Wash thoroughly after use. Remove contaminated clothing.
Occupational Exposure Limits: OSHA PEL 1000 ppm (2400 mg/m3), ACGIH TLV 500 ppm (TWA), STEL 750 ppm
Engineering Controls: Local exhaust ventilation, fume hoods, explosion-proof extraction.
Respiratory Protection: Use NIOSH-approved vapor respirator if concentration exceeds exposure limits.
Eye Protection: Chemical splash goggles or full-face shield.
Skin Protection: Nitrile or butyl rubber gloves, lab coats, apron.
Other Protective Measures: Eyewash fountain, safety shower in work area.
Appearance: Colorless, volatile liquid
Odor: Sweet, pungent
Odor threshold: 13-20 ppm
pH: Neutral
Melting Point: -95°C
Boiling Point: 56°C
Flash Point: -20°C (closed cup)
Evaporation Rate: Very fast (compared to butyl acetate)
Flammability: Highly flammable liquid and vapor
Vapor Pressure: 24 kPa at 20°C
Vapor Density: 2 (air = 1)
Relative Density: 0.79 g/cm3
Solubility: Miscible with water
Partition Coefficient: log Pow -0.24
Auto-ignition Temperature: 465°C
Decomposition Temperature: Not specified
Viscosity: Low (0.32 mPa·s at 25°C)
Chemical Stability: Stable under normal conditions.
Reactivity: Reacts with oxidizing agents producing fire or explosion hazards.
Conditions to Avoid: Excessive heat, sparks, open flames, static discharge.
Materials to Avoid: Chlorine, strong acids, bases, oxidizers, reducing agents.
Hazardous Decomposition: Carbon monoxide, carbon dioxide, acrid smoke.
Polymerization: Does not occur under recommended storage.
Acute Toxicity (Oral): LD50 (rat): 5800 mg/kg
Acute Toxicity (Inhalation): LC50 (rat, 4h): 76 mg/L
Affected Organs: Central nervous system, eyes, skin, respiratory system
Symptoms: Eye redness, irritation, dizziness, nausea, drowsiness, headache, if high concentration, possible unconsciousness
Skin: May cause dryness, cracking after repeated exposure.
Chronic Exposure: Prolonged or repeated exposure may cause dermatitis.
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA.
Mutagenicity / Teratogenicity: No conclusive evidence from studies on humans.
Ecotoxicity: Harmful to aquatic life at high concentrations. LC50 (fish, 96h): 5540mg/L (Oncorhynchus mykiss).
Persistence and Degradability: Readily biodegradable in air and water. Half-life in water: several days.
Bioaccumulation: Low potential. Bioconcentration factor (BCF): 0.69.
Mobility in Soil: High. Moves rapidly through soil.
Other Adverse Effects: Does not significantly contribute to ozone depletion or global warming.
Waste Treatment Methods: Dispose of as hazardous waste by incineration at licensed facility.
Contaminated Packaging: Triple rinse then offer for recycling or disposal as hazardous material.
Precautions: Do not release to environment. Follow local, state, and federal environmental regulations.
Transportation for Disposal: Use leak-proof containers clearly marked as hazardous.
UN Number: 1090
UN Proper Shipping Name: Acetone
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Marine Pollutant: No
Special Precautions: Avoid handling near ignition sources. Segregate from incompatible chemicals.
OSHA: Covered under Hazard Communication Standard (HCS)
TSCA: Listed in Toxic Substances Control Act Inventory
SARA Title III: Subject to Sections 302 (No), 311/312 (fire, immediate health hazard), 313 (Reporting required in some states)
RCRA Status: U002, hazardous waste
European Regulations: Listed in EINECS (200-662-2), subject to REACH requirements
Labeling Requirements: Danger, highly flammable, keep away from ignition sources, avoid contact with eyes and skin
Other Regulatory Info: State-specific requirements such as California Proposition 65 not applicable for acetone; check local guidance for workplace controls.
