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Product Name: 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic Acid
Synonyms: Trolox; Trolox acid
Recommended Uses: Antioxidant, laboratory reagent, reference standard
Chemical Formula: C14H18O4
Supplier: Standard laboratory chemical suppliers and chemical distributors
Emergency Contact: Refer to SDS provided by supplier for specific national emergency numbers
CAS Number: 53188-07-1
Hazard Class: Not classified as hazardous according to GHS
Physical Hazards: Fine powder can cause dust accumulation in air
Health Hazards: Prolonged contact may cause mild skin or eye irritation; ingestion may lead to gastrointestinal discomfort. Individuals with pre-existing allergies may experience greater sensitivity.
Environmental Hazards: Not expected to pose significant environmental hazards under normal conditions of use
Label Elements: No standard hazard pictograms assigned. Recommended precautions: avoid inhalation, wear suitable protective gear.
Chemical Name: 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic Acid
CAS Number: 53188-07-1
Concentration: >98% (technical/laboratory grade material)
Impurities: Less than 2% minor organic compounds, not believed to impact hazard profile
Inhalation: Remove person to fresh air, keep at rest, monitor for respiratory symptoms, seek medical attention if irritation persists.
Skin Contact: Wash area thoroughly with water and mild soap, remove contaminated clothing, consult medical provider if irritation develops.
Eye Contact: Rinse cautiously with water for at least 15 minutes, hold eyelids open, seek medical attention if redness or pain continues.
Ingestion: Rinse mouth, drink water for dilution, never induce vomiting unless instructed by medical personnel, consult a physician.
Acute Effects: No expected life-threatening effects, but immediate medical attention for persistent symptoms is recommended.
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jets
Specific Hazards: Material can release toxic fumes such as carbon monoxide and dioxide under fire conditions
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective clothing
Other Advice: Avoid inhalation of combustion products, keep containers cool with water spray if exposed to fire, evacuate area as needed
Personal Precautions: Wear gloves, safety goggles, laboratory coat, avoid dust formation and inhalation. Ensure adequate ventilation.
Environmental Precautions: Prevent from entering sewers or waterways. Use absorbent material to contain spill.
Clean-up Methods: Collect spilled material with inert absorbent (sand, vermiculite), transfer to chemical waste container, wash affected area with detergent and water. Dispose of contaminated materials in accordance with local and national regulations.
Handling: Operate in well-ventilated place, use personal protective equipment, avoid dust generation, prohibit eating and drinking near material. Practice good hygiene, wash hands after handling.
Storage: Store in tightly closed original container, keep in a cool, dry, well-ventilated area away from oxidizers and sources of ignition. Protect from moisture, sunlight, and excessive heat. Clearly label storage containers and avoid unnecessary handling.
Exposure Limits: No occupational exposure limits established for this compound
Engineering Controls: Use laboratory fume hood or local exhaust if dust or aerosols arise
Personal Protection: Wear chemical-resistant gloves (nitrile or rubber), safety goggles, laboratory coats. For larger scale or prolonged use, select a dust mask or respirator approved for particulates.
Environmental Controls: Use procedures that minimize environmental exposure, ensure spill containment equipment is available.
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: Approximately 137-140 °C
Boiling Point: Not available; decomposes before boiling
Solubility: Soluble in ethanol and DMSO, poorly soluble in water
pH (solution): Slightly acidic when dissolved in water
Vapor Pressure: Negligible at room temperature
Density: About 1.2 g/cm3
Flash Point: Not flammable under standard conditions
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Not reactive under normal laboratory conditions
Incompatibilities: Avoid contact with strong oxidizing agents and bases; may react to form peroxides or other hazardous compounds upon prolonged exposure.
Decomposition: Heating to decomposition releases carbon oxides, potentially hazardous fumes
Acute Toxicity: No acute toxicity data available for humans; structurally related compounds generally regarded as low-toxicity
Skin/Eye Contact: Mild irritation possible; rare reports of allergic reaction in sensitive persons
Ingestion/Inhalation: Not expected to be acutely hazardous by these routes at low laboratory levels; large amounts may cause discomfort
Sensitization: Not classified as a sensitizer based on available studies
Carcinogenicity/Mutagenicity: Not listed by OSHA, NTP, or IARC. No evidence supporting mutagenic or carcinogenic effects found in literature at standard laboratory concentrations.
Aquatic Toxicity: No data for this specific compound, but structure suggests low toxicity to aquatic organisms
Persistence/Degradability: Biodegradable in the environment. Breakdown products unlikely to cause long-term hazards.
Bioaccumulative Potential: Low potential for bioaccumulation based on water solubility and molecular structure
Mobility in Soil: Tends to remain in upper soil layers, low risk of groundwater contamination
Other Adverse Effects: Not anticipated under recommended handling; care should be taken to prevent uncontrolled releases
Disposal Methods: Collect and transfer material to hazardous or special waste collection area. Incinerate in authorized facility or landfilled in accordance with local, regional, and national regulations.
Container Disposal: Empty containers should be rinsed thoroughly, rendered unusable, and managed as hazardous waste if contaminated.
Precautions: Avoid discharge to environment, never dispose of down the drain or in household waste streams, consult with local disposal contractors or environmental agencies for proper disposal instructions.
UN Number: Not classified as hazardous for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not considered environmentally hazardous during transport
Special Precautions: Avoid generating dust during transport and loading; ensure container integrity
US Regulations: Not regulated as a hazardous substance under SARA, CERCLA, or RCRA. Not listed as a controlled substance.
EU Regulations: Not classified as hazardous according to Regulation (EC) No 1272/2008
Inventory Listings: Notified and/or listed on TSCA, REACH, EINECS/ELINCS
Worker Protection: General chemical hygiene and lab safety rules apply, including training in safe handling and emergency procedures.
Labeling Requirements: Label with product name, chemical identifier, hazard warnings, precautionary measures as a minimum standard of care.
