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Name: 6-Biopterin
Chemical Formula: C9H11N5O3
Molecular Weight: 237.22 g/mol
Synonyms: 6-Pterinamine-2,4-dione
Common Uses: Research laboratories, clinical and biochemical studies involving enzymatic cofactor functions.
Appearance: Pale yellow, crystalline solid, usually sold in sealed containers.
Physical Risk: Dust generated may irritate eyes, skin, or respiratory tract.
Health Risk: Contact can trigger mild irritation; ingestion and inhalation over short periods rarely cause lasting problems, but larger exposures should be avoided.
Environmental Hazards: Low estimated toxicity to aquatic species, not expected to accumulate significantly in the environment, but releasing unnecessary quantities into drains or soil can disturb local ecologies.
GHS Classification: Substance not broadly regulated as toxic, corrosive, or carcinogenic; always treat as potentially hazardous in lab settings.
Chemical Identity: Pure 6-Biopterin, typically sold as a single-component material without significant impurities in analytical grades.
CAS Number: 22150-76-1
Impurities: Trace water content, potential for minor unidentified by-products depending on storage or supplier.
Eye Contact: Rinse thoroughly with plenty of water for several minutes; seek medical advice if discomfort develops.
Skin Contact: Wash with gentle soap and water; remove contaminated clothing.
Inhalation: Move outdoors or to fresh air, avoid dust clouds; persistent symptoms require medical attention.
Ingestion: Rinse mouth with water; seek medical assistance if the person feels unwell.
Flammability: No history of spontaneous combustion at room temperature; decomposes under intense heat above 200°C.
Suitable Extinguishing Media: Use water spray, foam, carbon dioxide, or dry chemical.
Special Firefighting Gear: Firefighters should use standard protective gear, including self-contained breathing apparatus, in smoky or confined settings.
Combustion Byproducts: Potential for toxic nitrogen oxides and carbon oxides formation in incomplete combustion.
Personal Protection: Wear laboratory gloves, safety goggles, and dust mask or respirator if powder is disturbed.
Cleanup Method: Sweep up using gentle methods to avoid generating dust, place material in suitable waste container.
Decontamination: Rinse affected area with water; ventilate room.
Environmental Caution: Prevent powder from spreading into watercourses or soil; collect for proper disposal.
Handling: Avoid breathing dust; use only in well-ventilated areas or within fume hoods; keep away from oxidizing substances.
Storage: Keep tightly closed in light-resistant container, ideally at 2–8°C; minimize humidity and direct sunlight exposure.
Incompatibility: Avoid strong oxidants and acids.
Engineering Controls: Laboratories should use local exhaust ventilation, weighed powders inside safety enclosures.
Personal Protection: Gloves (nitrile recommended), safety goggles, laboratory coat; dust mask when handling large amounts.
Hygiene: Wash hands thoroughly after handling.
Occupational Limits: No established OSHA or ACGIH exposure limits; minimize exposure as a precaution.
Form: Crystalline powder
Color: Pale yellow
Odor: No significant odor
Melting Point: Decomposition begins around 220–230°C
Solubility: Low in water; solubility improves slightly in acidic solutions.
Stability: Relative stability at room temperature, sensitive to strong light and moisture.
Stability: Stable under recommended storage conditions; avoid sustained exposure to light and air to limit degradation over time.
Hazardous Reactions: May react strongly with oxidizing chemicals; avoid mixing.
Decomposition Products: Forms nitrogen oxides and possible carbon oxides under thermal decomposition.
Conditions to Avoid: Excessive heat, moisture, and oxidizing environments.
Routes of Exposure: Eyes, skin, inhalation, ingestion.
Acute Effects: Mild irritation to skin, eyes, respiratory tract reported in animal models.
Chronic Effects: No robust data on long-term toxicity in humans; chronic exposure uncommon in non-industrial settings.
Carcinogenicity: No classification by NTP, IARC, or EPA.
Mutagenicity and Teratogenicity: Lacking strong evidence of genetic or developmental hazards.
Environmental Fate: Expected to degrade slowly in air and water; not prone to bioaccumulation.
Aquatic Toxicity: No significant acute toxicity documented for typical environmental concentrations.
Soil Mobility: Limited water solubility suggests short migration distances.
Biodegradability: Slowly biodegradable.
Waste Treatment: Handle as laboratory chemical waste; do not pour into public sewage systems.
Disposal Method: Incinerate with compatible materials or send to licensed chemical waste facilities.
Environmental Protection: Prevent product reach into soil, drains, or waterways; always use local regulations as disposal guidance.
UN Number: Not classified as dangerous for transport under ADR, IATA, IMDG.
Packaging: Secure, light-resistant containers; prevent moisture infiltration.
Transport Hazards: Not expected to present significant risk if handled prudently during transport.
OSHA Status: Not specifically listed in US hazardous substance standards.
TSCA Status: Included in the Chemical Substance Inventory for research purposes.
REACH (EU): Low-volume chemical under research exemption reporting.
Other Regulations: Not subject to specific national restrictions, but always check state and international laboratory safety guidelines.
