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Material Safety Data Sheet for 6-Benzylaminopurine

Identification

Product Name: 6-Benzylaminopurine
Synonyms: BAP; Benzyladenine; 6-BA; N6-Benzyladenine
CAS Number: 1214-39-7
Recommended Uses: Plant growth regulator, tissue culture media supplement
Supplier: Please consult your product label for your supplier contact information and emergency phone numbers
Manufacturing Address: Provided by distributor upon request
Emergency Contact: Refer to regional poison control center or workplace supervisor

Hazard Identification

GHS Classification: Not classified as hazardous under GHS guidelines for general laboratory use; some products may offer irritation warnings
Physical Hazards: Dust can cause mechanical irritation to respiratory tract
Health Hazards: May irritate eyes, skin, or if inhaled; ingestion can upset gastrointestinal system
Environmental Hazards: Considered not acutely hazardous; high concentrations may affect aquatic organisms
Signal Word: None required according to most safety studies
Hazard Statements: Not expected to produce harmful systemic effects at low concentration; avoid excessive dust exposure
Precautionary Statements: Use suitable personal protective equipment; maintain good laboratory hygiene

Composition / Information on Ingredients

Chemical Name: 6-Benzylaminopurine
Common Name: 6-BAP
Concentration: Pure substance, 100% unless diluted for specific formulations
Molecular Formula: C12H11N5
Molecular Weight: 225.25 g/mol
Impurities: Typical lab-grade contains minor trace solvents or water (<1%) depending on storage and handling conditions

First Aid Measures

Inhalation: Move affected person to fresh air; seek medical attention if symptoms persist
Skin Contact: Wash thoroughly with soap and water for several minutes; remove contaminated clothing
Eye Contact: Rinse eyes immediately with plenty of water for at least 15 minutes; seek medical advice if irritation develops or persists
Ingestion: Rinse mouth with water; do not induce vomiting; seek advice from a medical professional
Advice for Medical Personnel: Provide symptomatic and supportive care; no specific antidote known

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, CO2, or foam for small fires
Unsuitable Media: High-pressure water streams may scatter powder
Fire and Explosion Hazards: May decompose upon heating to form toxic gases such as nitrogen oxides, carbon oxides
Protective Equipment: Wear self-contained breathing apparatus and full protective clothing
Special Precautions: Evacuate unprotected personnel from area; contain runoff to prevent dissemination into environment

Accidental Release Measures

Personal Precautions: Use personal protective equipment including gloves, lab coat, safety goggles, and dust mask
Environmental Precautions: Prevent spilled material from entering drains, waterways, or soil
Cleanup Procedures: Sweep up solid material gently; avoid creating dust; transfer to labeled, sealable container for disposal
Ventilation: Use only in well-ventilated areas to avoid dust buildup
Decontamination: Clean surface with water and mild detergent; avoid use of strong oxidizers

Handling and Storage

Handling: Avoid breathing dust and minimize direct contact; use only with local exhaust or proper fume hood
Safe Practices: Wash hands after handling and before eating or drinking; keep food away from work area
Storage Conditions: Store in a tightly closed container; keep in a cool, dry, ventilated area
Temperature Recommendations: Recommended storage temperature: 2–8°C (refrigerated) to prolong stability
Incompatibilities: Strong oxidizers, acids, and bases may cause decomposition or reduced stability
Special Packaging: Use containers made of glass or compatible plastics

Exposure Controls and Personal Protection

Engineering Controls: Utilize fume hoods, local exhaust, or general ventilation to control airborne dust
Personal Protective Equipment: Safety goggles, nitrile or latex gloves, laboratory coat recommended
Respiratory Protection: NIOSH-approved dust respirator if dust levels are elevated
Hygienic Measures: No consumption of food or drink in work area; change out of work clothing before leaving lab
Threshold Limit Value: Not established for pure 6-Benzylaminopurine
Biological Monitoring: Not routinely required under standard laboratory conditions

Physical and Chemical Properties

Appearance: White to slightly off-white crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH (1% aqueous): Typically neutral (pH 6–8 in solution)
Boiling Point: Decomposes before boiling
Melting Point: 230–233°C (with decomposition)
Flash Point: Not flammable under standard lab conditions
Solubility in Water: Slightly soluble (about 10–50 mg/L at 25°C); more soluble in dilute acid
Solubility in Solvents: Soluble in DMSO, DMF, ethanol; limited in water
Vapor Pressure: Negligible at ambient temperature
Density: 1.31–1.34 g/cm³
Partition Coefficient: logP ~1.4
Evaporation Rate: Not volatile

Stability and Reactivity

Stability: Stable under normal storage and handling conditions; avoid moisture ingress
Reactivity: Unreactive under normal laboratory settings; heating may cause decomposition
Conditions to Avoid: High temperatures, open flames, direct sunlight, strong acids or bases
Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide may form when heated or burned
Polymerization: Not known to undergo hazardous polymerization
Incompatibilities: Strong oxidizing agents and reducing agents may change product purity or enhance reactivity

Toxicological Information

Acute Toxicity: Low acute toxicity via oral, dermal, or inhalation routes in animal studies
LD50 (oral, rat): >2,000 mg/kg
Skin Irritation: Non-irritating under most test conditions; prolonged contact may cause mild redness
Eye Irritation: Dust can cause local irritation if it enters eyes
Respiratory Sensitization: Repeated exposure to high dust concentrations may irritate airways
Chronic Effects: Not identified as carcinogenic, mutagenic, or teratogenic in published data sets
Other Health Information: No known health effects from foreseeable laboratory exposure with proper PPE
Occupational Exposure Limits: No established limits for this product at this time

Ecological Information

Environmental Fate: Chemical degrades slowly in soil, especially under aerobic conditions
Mobility: Moderately mobile in water with low solubility
Bioaccumulative Potential: Unlikely to bioaccumulate based on structure and partition coefficient
Aquatic Toxicity: LC50 (fish, 96 h): >100 mg/L; EC50 (Daphnia, 48 h): >100 mg/L
Persistence and Degradability: Tends to persist in environment at high concentrations; rapid breakdown not expected
Soil Impact: Used widely in agriculture; no significant negative impact documented at normal use rates

Disposal Considerations

Waste Disposal Methods: Dispose as hazardous chemical waste according to local, regional, and national rules
Contaminated Packaging: Rinse thoroughly and follow approved procedures for chemical container recycling or disposal
Special Instructions: Do not allow product to enter sewers, surface water, or soil in bulk quantities
Incineration: Permitted with flue gas cleaning if approved facility is available
Additional Notes: Consult local environmental authorities for large-scale disposal or spill incident protocols

Transport Information

UN Number: Not regulated for transport under UN guidelines
Proper Shipping Name: 6-Benzylaminopurine
Transport Hazard Class: Not classified as dangerous for road, air, or sea transport
Packing Group: None assigned
Special Precautions: Prevent container damage and seal tightly to prevent spillage en route
Environmental Hazards: Not regulated as a marine pollutant
Additional Transport Information: Keep away from strong oxidizers and separate from foodstuffs during shipping

Regulatory Information

US TSCA: Listed
EU REACH: Registration not required for R&D amounts; check for national registration in the EU
Canadian DSL/NDSL: Not specifically listed; check with Health Canada for requirements
OSHA Classification: Non-hazardous under normal laboratory conditions
SARA Title III: Not subject to reporting
WHMIS Classification: Not listed as hazardous
Other Regulatory Status: Not restricted under the Stockholm or Rotterdam Conventions
Labeling Requirements: Standard chemical labeling required for workplace safety