© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Name: 4-Nitrophenyl Butyrate Chemical Formula: C10H9NO4 Common Uses: Substrate for esterase activity studies in biochemical research Synonyms: p-Nitrophenyl butyrate, PNB Appearance: Light yellow crystalline powder Typical Odor: Not easily detected by smell in small labs Recommended Use: Research, specifically enzyme kinetics and biochemistry labs Unintended Use: Outside of well-ventilated lab environments or without proper chemical handling routines
Potential Health Hazards: Skin and eye irritation, respiratory tract discomfort with dust, moderate toxicity if consumed Environmental Risks: May cause harm in aquatic systems Signal Word: Warning Routes of Exposure: Inhalation, accidental ingestion, skin and eye contact Alert Symptoms: Coughing, redness, itching, lacrimation, mild headaches in enclosed space
Main Ingredient: 4-Nitrophenyl Butyrate, purity usually above 98% in lab containers Impurities: Trace organic solvents used in synthesis, rare in finished product Molecular Weight: About 207.18 g/mol
Eye Contact: Rinse thoroughly with water, keep eyelids open, seek medical attention for redness or pain Skin Contact: Remove contaminated clothing, wash area with mild soap and water, consult health services if irritation stays Inhalation: Move to fresh air, offer oxygen if symptoms persist, medical evaluation if effects linger Ingestion: Rinse mouth, avoid forced vomiting, reach out to poison control or medical provider quickly
Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide Unusual Hazards: May release toxic fumes like nitrogen oxides and carbon oxides on burning Firefighter Protection: Use full protective gear and self-contained breathing support, avoid inhaling smoke or vapor Thermal Decomposition: May give off acrid smoke and nitrogen-containing gases, typically seen in poorly ventilated rooms
Personal Precautions: Avoid dust formation, ventilate area well, use gloves and eye shields Environmental Precautions: Prevent spilled material from reaching drains or soil Clean-up Methods: Sweep or vacuum up residue gently, collect in appropriate waste container, finish area cleaning with damp cloth, run exhaust fans if available
Safe Handling Tips: Store away from eating areas, use gloves and goggles, wash after use, avoid splashing Storage Conditions: Keep sealed in cool, dry spot, out of sunlight Incompatibles: Acids, strong oxidizers, open flames Storage Container: Use original or chemically resistant bottles, label with content and hazard icons
Ventilation: Use fume hoods or dedicated extraction fans Gloves: Nitrile or latex for regular tasks Eye Protection: Safety glasses, lab goggles for splash risk Respiratory Protection: Dust mask or P95 respirator for powder handling Lab Coats: Long-sleeve cotton or disposable outerwear, minimize skin exposure Hygiene: Wash hands after handling, keep food and drink out of the lab, keep surfaces clean after working with powders
Physical State: Solid Color: Light yellow Odor: Not significant at low concentrations Melting Point: Ranges from 52°C to 56°C Boiling Point: Data is scarce, unlikely to be relevant in standard lab situations Solubility: Slight in water, dissolves in alcohols and organic solvents like ethanol and DMSO Other Features: Stable in solid form, sensitive to strong acids and bases
Stability: Stable under dry, room temperature storage Reactivity: Reacts with bases and acids, reacts with some oxidizing agents Hazardous Decomposition: Releases nitrogen oxides and carbon-containing gases at high temperatures Polymerization: Not reported under standard lab conditions
Acute Toxicity: May irritate mouth, throat, and stomach if swallowed, acute data in published research Skin: Prolonged contact gives redness or dryness Eyes: Direct contact can sting, trigger tearing Long-Term Exposure: Limited published data on repeat exposure among humans, so err on safety Special Risks: People with impaired liver or kidney function may be more sensitive
Impact on Water: Known to affect aquatic invertebrates in test settings Mobility: Moves in water but sticks to soil particles, raising risk near riverbanks Persistence and Degradability: Moderate breakdown rate, likely to linger in surface water for weeks Bioaccumulation: Not much data, but similar nitrophenols build up in fish over time Aquatic Toxicity: Avoid letting it reach fish tanks or local water, especially in research setups near runoff
Lab Waste: Place in hazardous waste bin for organics Never Pour Down Drain: Local treatment systems can’t break it down fully Incineration: Preferable at licensed chemical disposal centers Empty Containers: Rinse, mark for hazardous chemical residue
Shipping Category: Transport as a chemical with moderate risk, avoid stacking or dropping containers Packing: Use secondary spill-proof boxes Internal Policies: Mark containers with proper labels, follow campus or agency guidelines International Laws: Shipments often require customs notification due to potential misuse in synthesis
Workplace Regulations: Covered by OSHA for chemical laboratory use Environmental Rules: Local and state agencies monitor for aquatic toxicity Listed Hazards: Not federally flagged, but rules on handling organics and hazardous byproducts always apply Reporting: Spills above reportable quantity get addressed through university or workplace environmental safety offices
