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Product Name: 4-Methyl-o-phenylenediamine
Synonyms: 2,3-Diaminotoluene, 1,2-diamino-4-methylbenzene
CAS Number: 95-80-7
Molecular Formula: C7H10N2
Molecular Weight: 122.17 g/mol
Manufacturer: [Company-specific data required]
Emergency Contact Number: [Company-specific data required]
Recommended Use: Dye intermediate, chemical research
Restrictions on Use: Non-consumer use, industrial settings only
GHS Classification: Acute Toxicity, Oral (Category 3); Skin Sensitization (Category 1); Eye Irritation (Category 2A); Carcinogenicity (Category 2)
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes serious eye irritation, may cause allergy or asthma symptoms or breathing difficulties if inhaled, may cause an allergic skin reaction, suspected of causing cancer
Precautionary Statements: Avoid all skin and eye contact, do not inhale dust or vapors, wear protective clothing, wash after handling
Label Elements: Skull and crossbones pictogram, exclamation mark pictogram, health hazard pictogram
Other Hazards: May release toxic fumes under fire conditions
Chemical Name: 4-Methyl-o-phenylenediamine
Purity: ≥ 98%
CAS Number: 95-80-7
Impurities: ≤ 2% unidentified impurities, typical results on COA
EC Number: 202-448-4
Component Contribution: Responsible for all listed health hazards in product form
General Advice: Seek medical attention immediately if symptoms occur.
Inhalation: Move person to fresh air, keep individual comfortable and breathing freely, do not induce vomiting, consult medical personnel swiftly.
Skin Contact: Remove contaminated clothing, rinse skin with running water for at least 15 minutes, seek medical advice.
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting eyelids occasionally to ensure complete removal, obtain medical assistance
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person, consult poison control
Symptoms: Possible symptoms include irritation, redness, rash, difficulty breathing, possible delayed reactions affecting bladder or kidneys
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Fire Hazards: Combustion releases carbon oxides, nitrogen oxides, and toxic vapors.
Special Protective Equipment for Firefighters: Use self-contained breathing apparatus and full turnout gear to prevent inhalation of toxic fumes.
Explosion Data: Avoid static discharge, powdered material may present explosion hazard when dispersed in air.
Other Information: Containers may rupture when exposed to heat due to buildup of pressure.
Personal Precautions: Evacuate area, ensure adequate ventilation, avoid breathing dust, wear suitable respiratory protection and appropriate personal protective equipment (PPE).
Environmental Precautions: Prevent entry into sewers, soil, and waterways, containment required when large quantities spill.
Cleanup Methods: Scoop or vacuum spilled material using non-sparking tools, avoid creating dust, collect in appropriate container for disposal, wash spill area with plenty of water while preventing runoff.
Disposal: Dispose of material and cleaning aids as hazardous waste according to local, regional and national regulations.
Handling: Operate in a chemical fume hood, utilize appropriate personal protective equipment including gloves, safety goggles, and lab coats, avoid all contact with skin, eyes, or clothing, utilize only with proper ventilation, never eat, drink, or smoke in work area, maintain good personal hygiene.
Storage Conditions: Store in a tightly closed container, keep container upright and protected from physical damage, store in a cool, dry, well-ventilated area away from incompatible substances such as strong acids and oxidizers, maintain separation from food and beverages.
Special Requirements: Clearly label storage location, retain original packaging, maintain inventory controls with dated inspections.
Incompatibilities: Avoid contact with reducing agents, strong oxidizers, acids, alkali metals.
Occupational Exposure Limits: No established OSHA or ACGIH exposure limits for 4-methyl-o-phenylenediamine, use lowest recommended safe practices.
Engineering Controls: Local exhaust ventilation, process enclosures, eyewash stations, and safety showers in close proximity.
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, long-sleeved chemical-resistant clothing, NIOSH-approved respirator if ventilation inadequate.
Hygiene Measures: Wash hands before breaks and at end of workday, keep PPE separate from personal clothing, launder contaminated clothing before reuse.
Environmental Exposure: Prevent further release into environment through effective containment.
Appearance: Off-white to pale yellow crystalline solid
Odor: Amine-like, faintly aromatic
Odor Threshold: Not established
pH: Not applicable (solid form)
Melting Point: 77 – 79 °C
Boiling Point: 282 – 285 °C
Flash Point: 140 °C (closed cup)
Flammability: Not classified as flammable but may form combustible dusts
Explosion Limits: No available data
Vapor Pressure: Negligible at ambient temperature
Solubility: Slightly soluble in water, more soluble in alcohols and ethers
Partition Coefficient (log Kow): 0.43
Decomposition Temperature: Decomposes above 250 °C
Chemical Stability: Stable under recommended storage conditions.
Reactivity: Reacts with oxidizers and strong acids to produce hazardous decomposition products.
Hazardous Reactions: May undergo violent reaction with strong oxidants, not compatible with nitrites.
Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides, aromatic amines.
Conditions to Avoid: Heat, flames, sparks, uncontrolled contact with incompatibles.
Polymerization: No hazardous polymerization expected.
Acute Toxicity: LD50 Oral (rat): 90 mg/kg, Harmful if swallowed
Skin Corrosion/Irritation: May cause moderate skin irritation, redness, allergic response
Serious Eye Damage/Irritation: Causes eye irritation, possible damage to eye tissue
Respiratory Sensitization: Possible allergic reactions from inhalation
Skin Sensitization: High probability of allergic reaction on contact
Carcinogenic Potential: Animal data suggest mutagenic and possibly carcinogenic effects
Target Organs: May impact bladder, kidneys, blood system on long-term exposure
Other Effects: Symptoms can include headache, nausea, and respiratory distress
Aquatic Toxicity: Expected to be harmful to aquatic organisms.
Persistence/Degradability: Not rapidly biodegradable in natural environments.
Bioaccumulative Potential: Low potential for bioaccumulation suggested by partition coefficient.
Mobility in Soil: May leach and migrate in moist conditions, increased risk of groundwater contamination.
Other Adverse Effects: Uncontrolled releases may seriously impact aquatic populations, disrupt biological wastewater treatment processes, fish kills reported in case studies at higher concentrations.
Waste Treatment Methods: Dispose as hazardous chemical waste following local, state, and federal regulations, incineration preferred in suitable facilities.
Contaminated Packaging: Handle empty containers as hazardous due to possible residue, triple rinse and puncture before disposal.
Additional Guidance: Do not discharge into sewers, landfills or water bodies, consult with licensed waste disposal contractor.
Transportation to Disposal: Use properly labeled, closed, and compatible containers for transfer to authorized disposal facility.
Special Precautions: Keep away from food or medicinal waste, do not attempt neutralization without expert guidance.
UN Number: UN 1674
UN Proper Shipping Name: o-Toluylenediamine
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: III
Labels: Toxic, Environmental Hazard
Special Precautions for Transport: Avoid direct contact, use sealed secondary packaging, keep documentation and labeling accessible, emergency response guide and spill control equipment required for shipments
Marine Pollutant: Yes, mark accordingly under IMDG code
Other Transport Requirements: Compliance with ADR, IMDG, IATA, and DOT standards needed if shipping internationally.
TSCA Inventory: Listed in the United States Toxic Substances Control Act inventory
SARA Title III: Not listed under Section 302, subject to reporting under Section 313 as a toxic chemical
OSHA: Mandates hazard communication and safety training for all handlers
California Proposition 65: Not listed as of current review, but status subject to change
REACH: Listed; subject to registration, safe handling, and reporting
WHMIS (Canada): Classified as D1A (very toxic material)
Chemical Weapons Convention: Not scheduled
Other Local/State Regulations: May be subject to additional state or municipal requirements, verify current local legislation
Workplace Labeling: Clear, unambiguous hazard labels required in all handling and storage areas, up-to-date MSDS should be accessible at point of use.
