© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: 4-Aminoantipyrine
Chemical Name: 4-Amino-1,5-dimethyl-2-phenylpyrazol-3-one
CAS Number: 83-07-8
Synonyms: 4-AAP, 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolinone
Recommended Use: Laboratory reagent, pharmaceutical intermediate, analytical chemistry applications
Company Identification: Manufacturing and distributing companies specializing in chemicals and laboratory supplies
Emergency Phone: Refer to local poison control center or company emergency contact
Hazard Class: Acute toxicity (oral), Skin sensitizer, Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation; May cause an allergic skin reaction
Precautionary Statements: Avoid inhalation of dust, prevent contact with skin and eyes, do not eat or drink while handling
Pictograms: Exclamation mark symbol, health hazard
Routes of Exposure: Ingestion, inhalation, skin, and eye contact
Chemical Identity: 4-Aminoantipyrine
PURITY: Greater than 98% by weight
CAS Number: 83-07-8
Impurities: Trace organic solvents, no significant hazardous impurities declared in standard commercial product
Inhalation: Move affected person to fresh air, keep warm and at rest, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, seek medical attention for irritation or prolonged contact
Eye Contact: Rinse with plenty of water for at least fifteen minutes lifting eyelids, consult a physician
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical assistance
Important Symptoms: Irritation, sensitization, possible allergic response
Advice for Doctor: Symptomatic treatment based on clinical judgment, no specific antidote available
Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray
Unsuitable Extinguishing Media: High pressure water jets
Hazardous Combustion Products: Carbon oxides, nitrogen oxides, toxic fumes
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Additional Advice: Avoid inhaling combustion gases, keep run-off out of sewers and waterways
Personal Protection: Wear impervious gloves, eye protection, dust respirator
Spill Handling: Sweep up without generating dust, place in suitable labeled containers for disposal
Environmental Precautions: Prevent entry into drains, water courses, and soil
Cleanup Methods: Ventilate area, vacuum or wet-method preferred to reduce airborne dust, decontaminate with detergent and water
Precautions for Handling: Avoid dust formation, wear suitable personal protective equipment, use only in well-ventilated areas
Safe Storage Conditions: Store in tightly closed containers, in a dry, cool, well-ventilated area away from incompatible substances
Special Requirements: Keep away from strong oxidizers, acids, bases; segregate from food and drink
Incompatibilities: Strong oxidizing agents, strong acids or alkalis
Workplace Exposure Limits: No specific occupational exposure limits established for this compound
Engineering Controls: Use local exhaust ventilation to minimize worker exposure
Personal Protection: Chemical splash goggles, lab coats, gloves resistant to chemicals, certified dust mask or respirator if powdered material
Hygiene Measures: Wash hands and face thoroughly after handling, do not eat, drink, or smoke in work area
Environmental Controls: Prevent further leakage or spillage if safe to do so
Appearance: Yellow to light brown crystalline powder
Odor: Odorless or slightly aromatic
Molecular Formula: C11H13N3O
Molecular Weight: 203.24 g/mol
Melting Point: 125-130°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, soluble in methanol, ethanol, chloroform
pH (1% Solution): Approximately neutral
Vapor Pressure: Not applicable (non-volatile solid at room temperature)
Density: 1.29 g/cm³
Partition Coefficient: Log Kow estimated at 0.38
Flash Point: Not available; combustible but not highly flammable
Auto-ignition Temperature: Not established
Explosive Properties: Not considered explosive
Chemical Stability: Stable under recommended storage conditions
Possibility of Hazardous Reactions: Not likely under normal circumstances, may react with strong oxidizers
Conditions to Avoid: Excessive heat, exposure to light, moisture
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, toxic organic fumes
Acute Toxicity: Oral LD50 (rat) reported in range 500 mg/kg to 2000 mg/kg (variable by sources), harmful if swallowed
Skin Contact: May cause irritation or allergic reaction
Eye Contact: May cause serious eye irritation and redness
Inhalation: Dust may irritate respiratory tract; avoid inhalation
Sensitization: May cause sensitization by skin contact
Long Term Effects: Chronic exposure data limited; risk of allergic or hypersensitivity reactions
Carcinogenicity: No evidence for carcinogenic effects in standard laboratory studies
Mutagenicity and Teratogenicity: Not classified as mutagenic or teratogenic by regulatory agencies
Other Information: Symptoms from exposure can include headaches, nausea, and dizziness in poorly ventilated areas
Aquatic Toxicity: Limited available data; potential for low to moderate toxicity to aquatic life
Persistence and Degradability: Partial biodegradation possible in soil and water; not rapidly degradable
Bioaccumulative Potential: Low, based on estimated Log Kow
Mobility in Soil: Moderate mobility; slightly water soluble
Other Adverse Effects: Avoid release into the environment; do not allow material to contaminate ground water or water courses
Waste Treatment Methods: Collect for chemical waste disposal according to local, regional, and national regulations
Hazardous Waste: Dispose as hazardous organic chemical
Contaminated Packaging: Decontaminate and recycle or dispose according to governmental regulations
Other Advice: Do not discharge to drains or the environment; professional waste handlers recommended
UN Number: Not classified as a dangerous good for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: None assigned
Packing Group: None assigned
Environmental Hazards: Not environmentally hazardous for transport purposes
Special Transport Precautions: Avoid generating dust during transportation, keep containers securely closed
OSHA Status: Not specifically regulated as hazardous
TSCA Inventory: Listed
REACH Registration: Subject to pre-registration in Europe
WHMIS Classification: D2B (Toxic material causing other toxic effects)
Labeling Requirements: Chemical name, hazard symbols, precautionary statements in accordance with regional requirements
Additional Information: Safety assessment needed before large scale work, maintain records of handling and disposal
Other Regulatory Aspects: Observe local occupational health and safety regulations, waste management laws, and environmental protection directives applicable to chemicals
