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Material Safety Data Sheet for 3-Indoleacetic Acid (IAA)

Identification

Product Name: 3-Indoleacetic Acid
Synonyms: Indole-3-acetic acid, IAA
CAS Number: 87-51-4
Molecular Formula: C10H9NO2
Recommended Use: Plant growth regulator, research chemical
Manufacturer/Distributor: Consult your supplier or laboratory
Contact Information: Phone and emergency numbers on product label
Product Code: Varies by supplier

Hazard Identification

Hazard Classification: Not classified as hazardous under GHS criteria in most locations
Signal Word: None assigned
Hazard Pictograms: Typically not required
Hazard Statements: May cause mild skin or eye irritation, dust may irritate respiratory tract
Precautionary Statements: Avoid inhaling dust or particles, minimize direct contact with skin and eyes
Potential Health Effects: Prolonged or repeated exposure may cause irritation
Environmental Hazards: Possible risk to aquatic environments if large quantities released

Composition / Information on Ingredients

Chemical Name: 3-Indoleacetic Acid
Common Name: IAA
CAS Number: 87-51-4
Concentration: 98–100% pure for laboratory/research grade
Impurities or Additives: Generally none significant for analytical preparation

First Aid Measures

General Advice: Remove to fresh air, keep warm and at rest
Inhalation: Move to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing
Eye Contact: Rinse carefully with water for at least 15 minutes, consult physician
Ingestion: Rinse mouth, drink water if conscious, never induce vomiting, get medical advice
Most Important Symptoms: Mild skin or eye irritation, coughing if dust inhaled
Notes for Doctor: Treat symptomatically, product lacks acute systemic toxicity data

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Avoid direct water stream on burning powder
Special Hazards from Fire: May produce toxic gases (nitrogen oxides, carbon monoxide and dioxide) when burning
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Stay upwind, avoid inhalation of combustion products

Accidental Release Measures

Personal Precautions: Avoid contact with skin and eyes, prevent dust formation
Protective Equipment: Use appropriate personal protective equipment, including gloves, goggles, and dust mask
Environmental Precautions: Avoid runoff into water systems, keep away from soil and drains
Cleanup Methods: Sweep up and shovel, keep in closed container for disposal
Reference to Other Sections: See Exposure Controls, Disposal Considerations for more

Handling and Storage

Safe Handling: Handle in a well-ventilated place, avoid breathing dust, wash hands after use
Conditions for Safe Storage: Store tightly closed in a cool, dry, well-ventilated area
Incompatible Materials: Strong oxidizing agents, strong bases
Storage Temperature: Store at room temperature, away from moisture and light
Packaging Materials: Keep in original container or tightly sealed chemical-resistant packaging

Exposure Controls and Personal Protection

Control Parameters: No exposure limits established by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation or laboratory fume hood to minimize exposure
Personal Protective Equipment: Wear chemical-resistant gloves, safety glasses or goggles, and lab coat
Respiratory Protection: Use dust mask or respirator in case of inadequate ventilation
Hygiene Measures: Avoid eating, drinking, or smoking during use, wash hands and face after handling

Physical and Chemical Properties

Form: Crystalline powder
Color: White to pale beige
Odor: Essentially odorless
Melting Point: 166–169°C (330–336°F)
Boiling Point: Decomposes before boiling
Solubility in Water: Slightly soluble (approx. 1.1 g/L at 25°C)
Solubility in Other Solvents: Soluble in ethanol, methanol, DMSO
pH: Slightly acidic in solution
Partition Coefficient (log Kow): 1.41
Vapor Pressure: Negligible at room temperature
Density: 1.4–1.5 g/cm³
Flash Point: Not established due to high melting point
Auto-ignition Temperature: Data not available
Decomposition Temperature: Above 180°C

Stability and Reactivity

Chemical Stability: Stable under normal laboratory conditions
Reactivity: May react with strong oxidizing agents
Hazardous Reactions: No hazardous polymerization
Conditions to Avoid: Excessive heat, contact with incompatible materials
Incompatible Materials: Strong bases and oxidizers
Hazardous Decomposition Products: May release nitrogen oxides and carbon oxides on heating

Toxicological Information

Acute Toxicity: Data limited; estimated low oral toxicity (LD50 rat >2000 mg/kg as reported in some sources)
Skin Corrosion/Irritation: May cause mild, transient irritation under direct prolonged contact
Eye Damage/Irritation: Dust or solid may cause irritation
Respiratory Sensitization: No data, but dust may irritate airways
Skin Sensitization: No data to suggest allergic effects
Chronic Toxicity: No reliable evidence for mutagenicity or carcinogenicity
Other Effects: Not listed as a reproductive toxin

Ecological Information

Acute Aquatic Toxicity: Data scarce, considered low toxicity to fish (LC50 > 100 mg/L)
Persistence and Degradability: Breaks down in soil by microbial activity, not considered persistent in the environment
Bioaccumulative Potential: Log Kow value suggests low to moderate potential
Mobility in Soil: Slight, limited solubility in water
Other Adverse Effects: Avoid large releases, respect aquatic environments

Disposal Considerations

Disposal Methods: Dispose as chemical waste in accordance with local, regional, and national regulations
Contaminated Packaging: Rinse containers before recycling or disposal
Special Precautions: Do not discharge large quantities to sewers or water bodies
Waste Codes: Not assigned US EPA RCRA waste code

Transport Information

UN Number: Not assigned
UN Proper Shipping Name: Not regulated as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Ensure containers remain tightly closed and protected from moisture during transit

Regulatory Information

Safety, Health and Environmental Regulations: Not listed as hazardous under US OSHA, Canadian WHMIS, or European REACH
Inventory Status: Listed on TSCA, EINECS/ELINCS, Canadian DSL, AICS
Other Compliance: Ensure compliance with local workplace safety and environmental legislation
Label Requirements: Use standard chemical hazard label indicating irritant potential