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Product Name: 3-Hydroxytyramine Hydrochloride
Synonyms: Dopamine Hydrochloride, 4-(2-Aminoethyl)benzene-1,2-diol hydrochloride
Chemical Formula: C8H12ClNO2
CAS Number: 62-31-7
Recommended Use: Laboratory chemicals, industrial research, active pharmaceutical ingredient
Supplier Information: Manufacturer’s address, contact phone, emergency contact, email for technical information, supplier certification details
Classification (GHS/CLP): Acute toxicity (oral, dermal), skin sensitizer, eye irritation, specific target organ toxicity
Label Elements: Signal word: Warning, hazard pictograms: exclamation mark, precautionary phrases for handling and exposure
Potential Health Effects: Inhalation can irritate airways, contact with eyes causes pain and redness, ingestion leads to nausea and vomiting, prolonged contact with skin brings on dermatitis or sensitization
Environmental Hazard: May disturb aquatic environments, bioaccumulation not likely but breakdown products should not enter waterways
Chemical Name: 3-Hydroxytyramine Hydrochloride
Concentration: 98-100% (variable as per supplier batch)
Impurities: Trace inorganic salts, water, typically under 1%
Molecular Weight: 189.65 g/mol
Relevant Purity Grades: USP, EP, analytical, research grade labels noted by supplier
General Advice: Remove source of exposure, assess airways for breathing and pulse, seek medical attention for any symptoms
If Inhaled: Move to fresh air, support breathing as necessary, consult doctor for persistent cough or shortness of breath
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, use emollient if irritation appears, seek care for persistent rash
Eye Contact: Rinse cautiously with water for several minutes, avoid rubbing, remove contact lenses, medical attention in case of redness, tearing
If Swallowed: Rinse mouth, do not induce vomiting, give water if conscious, call local poison control for guidance
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam extinguishers, avoid strong jets
Specific Hazards: Produces toxic fumes including nitrogen oxides, hydrochloric acid vapor, carbon monoxide on combustion
Protective Equipment: Full protective gear, self-contained breathing apparatus, keep containers cool with sprayed water
Fire Fighting Precautions: Remain upwind, prevent runoff from entering drains or waterways, evacuate area if significant fire
Personal Precautions: Use chemically resistant gloves, goggles, mask for dust particles, adequate ventilation to minimize inhalation risk
Spill Response: Absorb with inert material such as vermiculite or sand, transfer to closed chemical waste containers, use appropriate tools for cleanup
Environmental Precautions: Contain to prevent entry into soil, sewers or streams, notify local authorities for significant spillage
Disposal Procedures: Decontaminate equipment with water and detergent, follow local regulations for hazardous waste
Handling Guidelines: Minimize dust generation, do not eat, drink or smoke during use, keep work area well-ventilated, use only with appropriate protective clothing
Safe Storage: Store tightly sealed in original container, keep in cool, dry, dark location, ensure separation from incompatible substances such as strong oxidizers and acids
Incompatibilities: Oxidizing agents, mineral acids, strong bases, certain metals and catalytic agents
Storage Conditions: Room temperature, away from direct heat, label containers with hazard details clearly visible
Control Parameters: No established OSHA PEL or ACGIH TLV, workplace monitor suggested if handling bulk quantities
Engineering Controls: Operate in chemical fume hood or well-ventilated environment, use local exhaust if dust develops
Personal Protection: Gloves made of nitrile or neoprene, laboratory coat, splash resistant goggles, face shield for procedures likely to generate aerosols
Hygiene Measures: Wash hands after handling, remove contaminated clothing before leaving work area, avoid skin contact by keeping protective equipment intact
Appearance: White to off-white crystalline powder
Odor: Odorless or faint characteristic smell depending on storage
pH (1% in water): About 3-5
Melting Point: 250-260°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Highly soluble in water, slightly soluble in ethanol, negligible in chloroform or ether
Vapor Pressure: Not volatile at room temperature
Partition Coefficient (logP): -2.46 (estimated)
Stability: Stable under normal temperatures when protected from air and light
Chemical Stability: Product stable if kept away from air and moisture, degrade on prolonged exposure to light, air, or heat
Conditions to Avoid: Moisture, direct sunlight, incompatible substances
Hazardous Decomposition: Includes hydrogen chloride, carbon oxides, phenolic compounds, nitrogen oxides
Polymerization: Not reported to undergo dangerous polymerization
Incompatible Materials: Strong oxidizing agents, strong acids or alkalis, metals prone to catalytic reactions
Acute Toxicity: Oral LD50 in rat reported around 200 mg/kg, inhalation LC50 not well established; possible toxicity depends on dose and route
Routes of Exposure: Inhalation, ingestion, skin and eye contact produce different responses
Symptoms: Includes headache, rapid heartbeat, hypertension, nausea, sweating, confusion at higher doses
Chronic Effects: Repeated or prolonged contact may sensitize skin, no significant carcinogenic, mutagenic, or reproductive hazard found in available studies
Medical Conditions Aggravated: Heart disease, hypertension, psychiatric disorders worsen with overexposure
Other Effects: Allergic reactions possible for those predisposed to catecholamine hypersensitivity
Ecotoxicity: Not highly toxic to aquatic life at low concentrations but long-term accumulation in large spills threatens local flora
Persistence: Degrades in environment by photolysis and microbial action, half-life under neutral conditions usually short
Bioaccumulation: Not likely to bioaccumulate due to high water solubility and rapid breakdown
Mobility: High mobility in water, potential leaching in soil, spills may reach surface or groundwater
Other Issues: Decomposition creates inorganic salts that alter water pH and cause stress in sensitive aquatic organisms
Waste Treatment: Collect solid waste in tightly closed, properly labeled hazardous waste containers
Disposal Methods: Incinerate using chemical waste incinerator with afterburner and scrubber, avoid direct landfill or drain disposal
Container Disposal: Triple rinse containers before recycling or punctual hazardous disposal, puncture and crush if allowed by local regulation
Regulatory Compliance: Adhere to federal, state, and local environmental and waste requirements, keep documentation for review
UN Number: Not classified under major transport codes (DOT, IATA, IMDG), handle as regulated chemical for laboratory use
Proper Shipping Name: Not specifically listed, dispatch as “laboratory chemicals, n.o.s.” if applicable
Packaging: Leak proof, shatter-resistant containers, strong external packing for bulk or international shipping
Handling Precautions: Protect from physical damage, avoid extremes of temperature or pressure, label shipment for chemical hazard
Transport Hazard Class: Non-hazardous for transport in small quantities but check local regulation for limits
U.S. Regulations: Not listed by TSCA, SARA Title III or CERCLA, controlled for pharmaceutical and research use
EU Regulation: REACH status varies by concentration and use, notify authority for import or export in large volumes
Worker Protection: OSHA Laboratory Standard applies, employers to provide hazard communication and training
Other Country Controls: National regulations differ, some countries require import/export notification or additional licensing
Hazard Phrases: Handle with care, proper risk assessment, documentation to support safe use on file with regulators
