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Chemical Name: 2-Propanol
Synonyms: Isopropanol, Isopropyl Alcohol, IPA
CAS Number: 67-63-0
Recommended Use: Solvent, cleaning agent, disinfectant, industrial and laboratory use
Manufacturer: Listed on packaging or supplied documentation
Contact Information: Company address and emergency telephone number provided by supplier
Product Type: Liquid
UN Number: 1219
Relevant identified uses: Surface disinfection, industrial manufacturing, laboratory reagent
GHS Classification: Highly flammable liquid and vapor (Category 2), Eye irritation (Category 2A), Specific target organ toxicity — single exposure (Category 3, narcotic effects)
Signal Word: Danger
Hazard Statements: Causes serious eye irritation, may cause drowsiness or dizziness, highly flammable liquid and vapor
Pictograms: Flame, Exclamation Mark
Precautionary Statements: Keep away from heat/sparks/open flames/hot surfaces, use explosion-proof electrical/ventilating equipment, avoid breathing vapors, wear protective gloves and eye/face protection, wash hands thoroughly after handling
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
PPE Symbols: Eye protection, gloves, respiratory protection for inadequate ventilation
Substance: Pure 2-Propanol
Chemical Formula: C3H8O
Percent Purity: >99% (unless diluted or specified otherwise)
Impurities: Water (<1%), trace organic compounds (specifics based on manufacturer)
Other Components: None
Inhalation: Move victim to fresh air, keep at rest, seek medical attention if symptoms develop (like dizziness, headache, or nausea)
Skin Contact: Remove contaminated clothing, wash with plenty of soap and water, seek medical attention for irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, seek medical advice if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, seek immediate medical advice
Symptoms: Drowsiness, dizziness, eye redness or irritation, confusion, possible loss of coordination
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide (CO2), water spray
Inappropriate Extinguishing Media: Direct water jet (risk of spreading fire)
Specific Hazards: Vapors form explosive mixtures with air, burns with orange flame and dense smoke, containers may explode when heated
Advice for Firefighters: Wear self-contained breathing apparatus, use protective clothing to prevent exposure, cool fire-exposed containers with water spray
Decomposition Products: Carbon monoxide, carbon dioxide, acrid smoke
Personal Precautions: Evacuate area, ventilate, eliminate ignition sources, avoid inhalation and skin contact, use recommended PPE
Environmental Precautions: Prevent entry into sewers, surface water, groundwater, soil
Cleanup Methods: Use inert absorbent materials (sand, earth, vermiculite), collect in suitable containers for disposal, flush area with plenty of water if safe
Additional Guidance: Notify authorities in case of significant spillage, follow company procedures for spills
Handling: Avoid contact with eyes, skin, and clothing, use only in well-ventilated areas, ground/bond containers, open and handle away from sources of ignition
Technical Measures: Use explosion-proof equipment, prevent build-up of electrostatic charges
Storage: Store in a tightly closed container, cool, dry, and well-ventilated place, keep away from heat, sparks, open flames, strong oxidizers, and acids
Conditions to Avoid: Temperatures above 40°C, direct sunlight, poorly ventilated areas
Occupational Exposure Limits: ACGIH TLV – 200 ppm TWA, 400 ppm STEL; OSHA PEL – 400 ppm TWA
Engineering Controls: Local exhaust ventilation, process enclosure, fume hoods
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (nitrile, butyl rubber), flame-resistant clothing, face shield as needed, respirator for vapor/mist above limits
Hygiene Measures: Remove contaminated clothing, wash hands before eating or drinking, do not smoke near product
Appearance: Clear, colorless liquid
Odor: Alcohol-like, characteristic
Odor Threshold: 22 ppm
pH: Not applicable (neutral in water)
Melting Point/Freezing Point: -89°C
Initial Boiling Point/Boiling Range: 82.6°C
Flash Point: 11.7°C
Evaporation Rate: 2.3 (butyl acetate = 1)
Flammability: Highly flammable
Upper/Lower Flammability Limits: 2% – 12% (v/v in air)
Vapor Pressure: 43 mmHg at 20°C
Vapor Density: 2.1 (air = 1)
Relative Density: 0.785 (water = 1)
Solubility: Miscible with water
Partition Coefficient (n-octanol/water): 0.05
Auto-ignition Temperature: 399°C
Decomposition Temperature: Above 400°C
Viscosity: 2.43 mPa·s at 25°C
Chemical Stability: Generally stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: Mixing with strong oxidizing agents, acids, aldehydes, halogens can cause violent reactions or fire
Conditions to Avoid: Heat, flames, sparks, poor ventilation, sources of ignition
Incompatible Materials: Acids, oxidizers (hydrogen peroxide, chromic acid), halogens
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possibly formaldehyde in fire conditions
Acute Toxicity: Oral LD50 (rat): ~5,045 mg/kg
Inhalation LC50 (rat): 16,000 ppm (8h)
Skin LD50 (rabbit): 12,800 mg/kg
Likely Routes of Exposure: Skin, eyes, inhalation, ingestion
Symptoms: Central nervous system depression, dizziness, headache, nausea, vomiting, irritant to eyes and skin, large doses may cause unconsciousness or death
Chronic Effects: Long-term or repeated exposure can cause skin dryness or cracking, possible liver and kidney effects
Sensitization: Not reported
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Toxicity to Aquatic Life: EC50 (Daphnia magna): 13,299 mg/L (48h), LC50 (Fish, Pimephales promelas): 9,640 mg/L (96h)
Persistence and Degradability: Readily biodegradable, does not persist in environment
Bioaccumulation Potential: Low (log Kow 0.05)
Mobility in Soil: High, will move readily through soil to groundwater
Other Adverse Effects: High concentrations can deplete dissolved oxygen in aquatic environments
Waste Treatment Methods: Dispose of contents and container through licensed hazardous waste facility, avoid release to environment, do not pour into drains or sewers
Regulations: Comply with local, state, and federal laws
Recommended Disposal: Incineration in approved facility, consult waste disposal contractor for guidance
Empty Containers: Handle as hazardous, retain label until thoroughly cleaned
UN Number: 1219
UN Proper Shipping Name: Isopropanol
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Label Required: Flammable liquid (label 3)
Transport Precautions: Secure packaging, prevent leakage, keep away from heat/sources of ignition, follow national and international transportation regulations (DOT, IATA, IMDG)
Special Transport Documentation: Emergency response information, shipping papers as required by carrier and country
United States: TSCA (listed), CERCLA (no reporting required), SARA 313 (not listed), OSHA Hazard Communication Standard 29 CFR 1910.1200 (hazardous)
Canada: WHMIS Classification: B2 (Flammable Liquid), D2B (Toxic material causing other toxic effects)
Europe: REACH registered, subject to Regulation (EC) No. 1907/2006, included in EINECS (200-661-7)
Other Regulations: Complies with country-specific chemical safety, transport, and environmental management controls
Labeling Requirements: GHS/CLP compliant labeling, hazard and precautionary statements on all packaging
