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Chemical Name: 2-Methylpyrazine
Chemical Formula: C5H6N2
Common Uses: Used in flavors, fragrances, and as a chemical intermediate in synthesis for pharma and other fine chemicals.
Odor: Nutty, toasted, chocolate-like aroma
Appearance: Colorless to pale yellow liquid or solid, depending on temperature
Molecular Weight: 94.12 g/mol
Hazards: Flammable liquid and vapor under typical storage and usage conditions. Slightly toxic if ingested or inhaled. Can irritate eyes and skin. May form hazardous decomposition products during a fire.
Signal Word: Warning
Risk Phrases: Irritating to eyes, respiratory system, and skin. Combustion can release toxic gases.
Potential Effects: Overexposure can cause headache, nausea, dizziness, or drowsiness. Extended contact with skin or inhalation can intensify symptoms.
Exposure Symptom: Coughing, eye irritation, mild tearing, and sore throat on inhalation.
Main Component: 2-Methylpyrazine
CAS Number: 109-08-0
Concentration: Typically supplied as nearly pure for industrial and research purposes.
Inhalation: Remove person to fresh air. If symptoms persist, seek medical attention.
Skin Contact: Wash area thoroughly with soap and water. Remove contaminated clothing. Seek attention if irritation develops.
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contact lenses if present and easy to do. Get medical help if irritation continues.
Ingestion: Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide. Water may be used for cooling containers exposed to flames but may not extinguish the fire.
Fire Hazards: Vapors may travel and ignite at distant sources. Burning produces irritating, toxic fumes.
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective gear.
Special Considerations: Approach from upwind to avoid vapor exposure.
Spill Management: Evacuate unnecessary personnel. Ventilate the area. Avoid breathing vapors. Wear appropriate protective equipment.
Containment: Absorb spills with inert material like sand or earth. Transfer to a container for disposal.
Environmental Precautions: Prevent entry into sewers, groundwater, or waterways. Clean up spills promptly.
Handling: Work in a well-ventilated area. Prevent vapor formation or accumulation. Use personal protective equipment as required.
Storage: Store in tightly closed containers in cool, dry, well-ventilated spaces away from ignition sources and incompatible chemicals. Keep away from oxidizing agents and strong acids.
Ground Properly: Bond and ground containers when transferring to prevent static discharge.
Engineering Controls: Use local exhaust or general room ventilation to keep airborne levels below recommended workplace limits.
Personal Protective Equipment: Safety glasses with side shields, chemical-resistant gloves, flame-retardant lab coat, and proper respiratory protection if ventilation is inadequate.
Hygiene Measures: Wash hands after handling and before eating or drinking. Avoid contact with eyes and skin.
Respiratory Protection: In case of inadequate ventilation, use respirators with suitable filters.
Form: Liquid or crystalline solid under normal conditions
Color: Colorless to pale yellow
Melting Point: About 12°C
Boiling Point: About 136°C
Flash Point: Approximately 39°C (closed cup)
Vapor Pressure: Moderate at room temperature
Solubility: Soluble in water, ethanol, and ether.
Odor Threshold: Low, sharp characteristic smell.
Stability: Stable under recommended storage and handling conditions. Sensitive to strong oxidizing agents.
Reactivity: Reacts with oxidizers and strong acids. Combustible vapors may form mixtures that ignite.
Decomposition: Will break down under fire conditions, releasing nitrogen oxides and carbon monoxide.
Routes of Exposure: Inhalation, skin, and eye contact
Acute Toxicity: Low to moderate toxicity by oral or dermal routes. May cause headaches, dizziness, or nausea when inhaled.
Irritation: Can irritate skin, eyes, and upper respiratory tract.
Long-Term Exposure: Limited data, but chronic exposure may exacerbate existing respiratory or skin disorders.
Sensitization: No known data to suggest allergenicity.
Carcinogenicity: Not classified as carcinogenic by standard international regulatory lists.
Aquatic Impact: Toxic to aquatic organisms in moderate concentrations. Not readily biodegradable.
Bioaccumulation: Potential for accumulation in aquatic food webs is low to moderate.
Persistence: Tends to persist if released in large amounts but diluted by water movement.
Other Effects: Can cause reduction in water quality around industrial discharge or accidental spills.
Waste Management: Collect waste in properly labeled containers. Dispose of through licensed chemical waste contractors.
Disposal Methods: Incinerate in approved facilities. Do not discharge to water systems or general trash.
Precautions: Follow regional, national, and local regulations for hazardous substances.
UN Number: Not always classified by a UN number in small laboratory quantities.
Transport Hazard Class: Flammable liquid classification if shipped in larger quantities.
Packing Group: III
Shipping Precautions: Use tight, impact-resistant containers. Label properly to indicate flammable hazards.
Special Instructions: Keep away from heat, open flames, and incompatible chemicals during transit.
Regulation Status: Listed on common chemical inventories such as TSCA, EINECS, and in local chemical inventories.
Occupational Exposure Limits: No established regulatory exposure limits in most regions; good practice requires minimizing exposure.
Worker Protection: Employers required to communicate chemical hazards to affected employees and provide training on chemical safety based on hazard type.
Community Right-To-Know: Reportable under certain local or national hazardous chemical regulations if stored in significant amounts.
