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Product Name: 2-Chlorofluorescein
Synonyms: 2-Chloro-3',6'-dihydroxyfluoran
CAS Number: 518-40-1
Recommended Use: Laboratory research, staining agent
Supplier: Contact appropriate manufacturer or distributor for details
Emergency Phone: Refer to local regulations and company procedures
Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin irritation
GHS Label Elements: Danger symbol, Signal word: Warning
Hazard Statements: Harmful if swallowed or inhaled. May cause skin and severe eye irritation.
Precautionary Statements: Avoid breathing dust, wear protective gloves/clothing/eye protection, wash thoroughly after handling
Chemical Name: 2-Chlorofluorescein
CAS Number: 518-40-1
Concentration: >98% (typical for reagent grade, confirm with supplier)
Impurities: Trace amounts of structurally related dyes or solvent residues, low-level degradation products may be present in old stock
Inhalation: Move exposed person to fresh air, seek medical attention for persistent symptoms, ensure open airways
Skin Contact: Remove contaminated clothing, rinse affected skin with soap and water, medical advice recommended for persistent irritation
Eye Contact: Rinse with plenty of water for at least 15 minutes, remove contact lenses if present,
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical care
Suitable Extinguishing Media: Dry chemicals, carbon dioxide, foam, avoid high-pressure water streams
Specific Hazards: Heating can produce toxic fumes (chlorine-containing, carbon oxides)
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Additional Advice: Stay upwind, use water spray to cool containers exposed to fire
Personal Precautions: Avoid dust formation, ventilate area, use appropriate personal protective equipment
Environmental Precautions: Prevent entry to drains, surface water, or soil
Cleanup: Sweep up and collect material in suitable, closed containers, wash area with water after removal
Disposal: Handle collected waste according to local, state, and federal laws
Handling: Work in a chemical fume hood, avoid direct contact with substance, keep containers tightly sealed, do not breathe dust
Storage: Store in original container, in a cool dry place, away from incompatible substances such as strong oxidizers and acids, limit exposure to light and moisture, keep away from ignition sources
Control Parameters: No established occupational exposure limits; minimize airborne particles with engineering controls
Engineering Controls: Local exhaust ventilation and general laboratory ventilation
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, laboratory coat
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke during use, maintain good housekeeping
Appearance: Yellow-green crystalline powder
Odor: Odorless or very faint
Melting Point: Approximately 273°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, more soluble in alcohol and alkaline solutions
Flash Point: Not applicable (non-flammable solid)
Vapor Pressure: Negligible at room temperature
pH: Varies based on solution, substance behaves as a weak acid in water
Other Properties: Stable under normal laboratory conditions; color may fade with light or prolonged storage
Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive with most common materials under normal use
Incompatible Materials: Strong oxidizers, acids, reducing agents
Decomposition Products: May release HCl and carbon oxides if heated to decomposition
Hazardous Polymerization: Not expected
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; precise LD50 values not widely reported
Skin Corrosion/Irritation: May cause irritation, redness, or dryness
Eye Damage/Irritation: Causes serious eye irritation, risk of corneal injury
Sensitization: No evidence of skin sensitization in available studies
Chronic Effects: Long-term exposure may impact respiratory and skin health
Carcinogenicity: No data to suggest carcinogenic potential in humans
Other Toxicity data: Not classified as mutagenic or reproductive toxicant based on available research
Aquatic Toxicity: Limited specific data; similar compounds have moderate toxicity toward aquatic organisms
Persistence and Degradability: Likely to persist under certain conditions, breakdown enhanced by sunlight and microbial activity
Bioaccumulative Potential: Unknown, expected to be low due to water solubility
Mobility in Soil: Potential mobility if spilled; bind to soil based on chemical structure
Other Adverse Effects: Avoid uncontrolled release to the environment; no evidence of ozone depletion or significant ecosystem disruption has been reported
Waste Treatment Methods: Dispose of unused product and contaminated material in accordance with all applicable regulations
Hazardous Waste Codes: Classified under laboratory chemicals, require incineration or chemical treatment
Packaging Disposal: Decontaminate and dispose of packaging as hazardous solid waste
UN Number: Not assigned (not regulated for most modes of transport, confirm with local authorities)
Proper Shipping Name: 2-Chlorofluorescein, laboratory chemical
Transport Hazard Class: Not classified as dangerous for transport
Packing Group: Not regulated for packing
Special Precautions: Avoid transport with food and feed, use sealed packaging
Environmental Hazards: Not classified as marine pollutant
TSCA (Toxic Substances Control Act): 2-Chlorofluorescein listed for chemical use
REACH Status: Exempt for laboratory use, not subject to full registration
OSHA: No workplace exposure limit established
WHMIS Classification: D2B - Toxic Material Causing Other Toxic Effects
SARA Title III: Not listed as a hazardous substance
Additional Regulations: Users should review local, state, and federal regulatory requirements for laboratory chemicals, especially in waste management and workplace safety
