Chemical Name: 2-Chloroethanol
Common Names: Ethylene chlorohydrin, Glycol chlorohydrin
CAS Number: 107-07-3
Molecular Formula: C2H5ClO
Molecular Weight: 80.52 g/mol
Use: Intermediate in organic synthesis, solvent, pesticide manufacture, plasticizer production, fumigant precursor
Supplier Information: Manufacturer contact details, address, emergency phone numbers
Recommended Use Restrictions: For industrial and laboratory use only; not for consumer use
Classification: Acute Toxicity (Oral) Category 3, Acute Toxicity (Dermal) Category 3, Skin Irritant Category 2, Eye Damage/Irritation Category 1, Specific Target Organ Toxicity (Single Exposure) Category 2
Pictograms: Skull and crossbones, corrosive symbol, exclamation mark
Signal Word: Danger
Hazard Statements: Toxic if swallowed, in contact with skin, or inhaled; causes severe skin burns and eye damage; may cause damage to organs
Precautionary Statements: Avoid breathing vapors; wash hands thoroughly after handling; do not eat, drink, or smoke when using; wear protective gloves, clothing, and eye protection
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Burning sensation, cough, shortness of breath, headache, nausea, convulsions, abdominal pain, loss of consciousness
Substance: 2-Chloroethanol
Concentration: ≥99%
Chemical Identity: 2-Chloroethanol
CAS Number: 107-07-3
Impurities or Stabilizers: None significant at standard purity; trace levels of water or by-products may accumulate during storage
Inhalation: Move person to fresh air, keep at rest, call poison center or doctor immediately; provide artificial respiration if not breathing
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, seek urgent medical advice
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes while holding eyelids open, seek immediate ophthalmologist evaluation
Ingestion: Seek immediate medical attention; rinse mouth, do not induce vomiting; never give anything by mouth to an unconscious person
Symptoms Requiring Attention: Labored breathing, severe irritation, signs of shock or confusion, persistent vomiting, altered mental status
Advice to Doctor: Monitor vital signs, consider gastric lavage if patient is conscious and recent ingestion, treat symptomatically
Flammability: Flammable liquid and vapor
Flash Point: 41°C (105.8°F)
Suitable Extinguishing Media: Water spray (fog), foam, dry chemical, carbon dioxide
Specific Hazards: Releases toxic and corrosive fumes including hydrogen chloride and phosgene in fire conditions
Protective Equipment: Full protective gear including self-contained breathing apparatus required for firefighters
Firefighting Procedures: Evacuate area, cool containers with water spray, prevent runoff from entering drains or waterways
Personal Precautions: Evacuate unnecessary personnel, ventilate area, wear chemical-resistant gloves, goggles, and respirator
Environmental Precautions: Prevent entry into waterways, soil, and sewers
Containment: Stop leak if safe to do so, contain spill with non-combustible absorbent (sand, earth, vermiculite)
Clean-Up Methods: Collect residue in sealable, clearly labeled containers for disposal, wash surface with detergent and water; ventilate area after clean-up
Decontamination: Use appropriate cleaning solutions, avoid re-contamination
Handling Precautions: Use only with adequate ventilation, avoid contact with skin, eyes, and clothing; do not breathe vapors; always wash hands after handling
Storage Conditions: Store in cool, dry, well-ventilated area away from incompatible materials (oxidizers, acids, alkalis, amines); keep container tightly closed and clearly labeled
Incompatibilities: Avoid contact with strong bases, strong acids, strong oxidizing agents, amines, and aluminum
Packaging Materials: Use corrosion-resistant containers (stainless steel, glass); avoid aluminum packaging
Special Considerations: Keep away from heat, sparks, open flames, and direct sunlight
Exposure Limit Values: OSHA PEL (TWA): 5 ppm (16 mg/m³), ACGIH TLV: 1 ppm (3 mg/m³)
Monitoring Procedures: Regular air monitoring, workplace exposure assessment
Engineering Controls: Use fume hoods, chemical exhaust ventilation, process enclosures
Personal Protective Equipment: Chemical-resistant gloves (nitrile or butyl rubber), safety goggles or face shield, impervious clothing, suitable respirator in absence of adequate ventilation
Hygiene Measures: No eating or drinking in work area, wash hands and face before breaks and at end of the shift, immediate removal of contaminated clothing
Appearance: Colorless to pale yellow liquid
Odor: Mild, sweet, ether-like
Odor Threshold: Not available
pH: Not applicable (neutral in pure form)
Melting Point: -70°C (-94°F)
Boiling Point: 128°C (262°F)
Flash Point: 41°C (105.8°F) (Closed cup)
Evaporation Rate: 0.18 (butyl acetate = 1)
Flammability: Flammable liquid, category 3
Vapor Pressure: 10 mmHg at 20°C
Vapor Density: 2.8 (air = 1)
Relative Density: 1.2 (water = 1)
Solubility: Completely soluble in water
Partition Coefficient (log Kow): -0.21
Auto-ignition Temperature: 410°C (770°F)
Decomposition Temperature: Not explicitly reported; decomposes under fire conditions
Viscosity: 2.68 mPa·s at 25°C
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: May react vigorously with strong oxidizing agents, acids, alkalis, amines, and aluminum
Possibility of Hazardous Reactions: Can polymerize or decompose exothermically under heat, exposure to light, or in presence of metals
Conditions to Avoid: High temperatures, exposure to open flames or sparks, contact with incompatible substances
Incompatible Materials: Strong oxidizers, strong bases, strong acids, amines, aluminum
Hazardous Decomposition Products: Releases toxic vapors including hydrogen chloride, carbon monoxide, carbon dioxide, phosgene on burning or decomposition
Acute Toxicity: Oral LD50 (rat): 140 mg/kg, Dermal LD50 (rabbit): 250 mg/kg, Inhalation LC50 (rat, 4h): 420 ppm
Skin Corrosion/Irritation: Causes severe burns
Serious Eye Damage/Eye Irritation: Causes severe eye damage
Respiratory or Skin Sensitization: Not sensitizing by established data
Germ Cell Mutagenicity: In vitro tests show mutagenic effects
Carcinogenicity: Not classified as carcinogenic to humans by IARC, NTP, or OSHA
Reproductive Toxicity: No conclusive data
Target Organ Effects: Central nervous system, kidneys, liver
Other Effects: Chronic exposure can result in motor and neurological symptoms, liver and kidney impairment
Aquatic Toxicity: LC50 (fish, 96h): 58 mg/L (fathead minnow), EC50 (daphnia, 48h): 98 mg/L; Acute toxicity to aquatic organisms
Persistence and Degradability: Readily biodegradable in environment
Bioaccumulation Potential: Not expected; low log Kow (-0.21)
Mobility in Soil: Mobile; leaches into soil and groundwater due to high solubility
Other Ecological Effects: Toxic to aquatic life in high concentrations; breakdown can contribute to groundwater contamination
Precautions: Prevent spills from reaching waterways or soil
Waste Treatment Methods: Incineration in approved facility preferred; do not release to environment
Disposal of Packaging: Triple rinse empty containers, puncture, and dispose of according to local, state, and federal regulations
Unusable Product Disposal: Contact licensed hazardous waste contractor
Precautions: Do not re-use empty containers for food or drink; avoid dispersal of spilled material, runoff, and contact with soil, waterways, drains, and sewers
UN Number: UN 1135
UN Proper Shipping Name: Ethylene chlorohydrin
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II (medium danger)
Labels Required: Toxic, Flammable
Marine Pollutant: No
Special Transport Precautions: Secure, upright containers; segregate from foodstuffs and oxidizing materials; compliance with national and international transport regulations
Transport Emergency Cards: Instructions for authorities and haulers in event of road or rail accident
U.S. Regulations: Listed in TSCA Inventory; OSHA, CERCLA, SARA Title III Section 313 reportable; subject to EPA hazardous substance regulations
EU Regulations: Classified under Regulation (EC) No. 1272/2008 (CLP); requires safety data sheets in accordance with REACH
Canada: Listed on the Canadian DSL/NDSL; subject to WHMIS regulations
Other International: Subject to national chemical control and workplace safety regulations; consult local, national, and international rules for further details
Labeling Requirements: Proper hazard pictograms, signal words, hazard, and precautionary statements in accordance with GHS