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Product Name: 1,2,4,5-Tetrachloro-3-nitrobenzene
Synonyms: Tetrachloronitrobenzene, TCNB
Chemical Formula: C6Cl4NO2
CAS Number: 117-18-0
Recommended Uses: Intermediate in chemical synthesis, specialty chemical research
Supplier Contact: [Insert complete address and emergency phone number]
Emergency Overview: Solid compound with yellowish appearance, faint chemical odor
Manufacturer: [Insert identifier]
UN Number: 3077
Recommended Use Restrictions: Industrial and laboratory applications only, not for consumer use
Classification according to GHS: Acute Toxicity (Oral), Category 4; Eye Irritation, Category 2; Skin Sensitization, Category 1; Aquatic Chronic, Category 2
Pictograms: Exclamation mark, Environment, Health hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin and eye irritation; may cause allergic skin reaction; toxic to aquatic life with long lasting effects
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; use only outdoors or in well-ventilated areas; avoid release to the environment; wear protective gloves, eye and face protection; if skin irritation or rash occurs, get medical advice
Routes of Exposure: Ingestion, inhalation, skin and eye contact
Most Serious Hazards: Causes irritation to eyes, skin, and respiratory system; long-term exposure may affect liver and kidneys; presents significant environmental toxicity
Chemical Name: 1,2,4,5-Tetrachloro-3-nitrobenzene
CAS Number: 117-18-0
Content by Weight: 98 – 100%
Impurities/Additional Ingredients: Minor process residues of related chlorinated nitrobenzenes (<2%)
Molecular Weight: 260.89 g/mol
Physical Description: Pale yellow crystalline solid
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, keeping eyelids apart.
Skin Contact: Remove contaminated clothing; wash skin with soap and water thoroughly; seek medical attention if irritation or rash develops.
Inhalation: Move person to fresh air; if symptoms persist, get medical attention; provide oxygen if breathing is difficult.
Ingestion: Rinse mouth with water if conscious; do not induce vomiting; seek immediate medical attention.
Most Important Symptoms: Eye and skin irritation, respiratory discomfort, gastrointestinal upset if swallowed
Suitable Extinguishing Media: Dry chemical powder, CO₂, water spray, foam
Specific Hazards: Combustion can produce toxic gases including hydrogen chloride, nitrogen oxides, phosgene.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective gear
Special Procedures: Use water spray to cool containers; avoid inhaling fumes or vapors; keep runoff out of waterways
Flammability: Not classified as flammable, but may emit hazardous fumes in case of fire
Explosion Hazards: No known explosion hazard under normal handling and storage conditions
Personal Precautions: Evacuate area; wear respirator, gloves, chemical-resistant clothing; avoid contact with spilled material
Environmental Precautions: Prevent entry into sewers or waterways; inform authorities if significant spill occurs
Methods for Clean Up: Collect spillage with non-sparking tools; place in tightly sealed, labeled containers for disposal; ventilate area; wash contaminated surfaces thoroughly
Emergency Procedures: Stop further release if safe to do so; isolate hazard area; restrict access to authorized personnel
Safe Handling: Avoid dust generation; use local exhaust ventilation; wear appropriate personal protective equipment; wash hands before eating or drinking
Storage Conditions: Store in tightly sealed containers, away from incompatible materials (strong bases, reducing agents); keep in cool, dry, well-ventilated place
Incompatibilities: Strong bases, oxidizers, reducing agents
Storage Class: Non-combustible solid hazard
Recommended Container Materials: Glass, high-density polyethylene, chemical-resistant-lined steel
Occupational Exposure Limits: No OSHA PEL or ACGIH TLV specified; minimize exposure as low as reasonably achievable
Engineering Controls: Use enclosures, local exhaust ventilation, and process isolation
Eye Protection: Safety goggles or face shield
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), lab coat, protective clothing
Respiratory Protection: Dust mask or cartridge respirator (if airborne dust present), follow NIOSH recommendations
General Hygiene: Do not eat, drink, or smoke in use areas; wash thoroughly after handling
Physical State: Solid
Appearance: Pale yellow crystalline powder
Odor: Faint aromatic odor
Melting Point: 182-185°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water; soluble in acetone, ethanol, ether
Specific Gravity: 1.8–2.0 (approximate)
Vapor Pressure: Negligible at room temperature
pH: Not applicable (insoluble)
Partition Coefficient (log Kow): 3.5 to 4.5 (estimated)
Flash Point: Not determined (solid, non-flammable)
Decomposition Temperature: Above 200°C
Volatility: Negligible
Viscosity: Not applicable (solid)
Chemical Stability: Stable at room temperature under normal conditions
Reactivity: May react with strong bases or reducing agents
Hazardous Reactions: No hazardous polymerization expected
Conditions to Avoid: Excessive heat, open flames, incompatible materials
Incompatible Materials: Strong alkali, reducing agents, strong acids
Hazardous Decomposition Products: Hydrogen chloride gas, phosgene, nitrogen oxides, carbon oxides
Acute Toxicity: Oral LD50 (rat): estimated 300-1500 mg/kg
Skin Irritation: Causes irritation based on animal studies
Eye Effects: Irritating to eyes; possible risk of corneal injury
Skin Sensitization: May cause allergic skin reaction in certain individuals
Inhalation Effects: Dust causes upper respiratory tract irritation; prolonged exposure may cause sore throat, coughing
Long-term Effects: Potential kidney and liver injury with repeated or prolonged exposure
Carcinogenicity: Not listed as a carcinogen by NTP, IARC, OSHA
Mutagenicity/Teratogenicity: Data not sufficient; use caution, avoid chronic exposure
Symptoms of Overexposure: Burning of eyes and skin, rash, respiratory distress, headache, nausea, dizziness
Toxicity to Aquatic Life: Toxic to aquatic organisms; may cause long-term damage in aquatic environments
Persistence and Degradability: Not readily biodegradable; persists in soil and water
Bioaccumulation Potential: Moderate; potential to accumulate in organisms
Mobility in Soil: Low solubility; binds to soils and sediments
Aquatic Toxicity Values: LC50 (Fish, 96h): estimated <1 mg/L
Other Adverse Effects: Disrupts aquatic food chains; harmful effects seen in algae, daphnia, and fish
Effects on Terrestrial Organisms: Not well studied; likely low mobility but toxic to soil microorganisms
Waste Management: Dispose of product and contaminated materials as hazardous waste
Recommended Disposal Methods: Incineration in chemical incinerator equipped with afterburner and scrubber; no disposal in regular trash
Contaminated Packaging: Treat as hazardous waste; do not reuse containers
Special Instructions: Follow all local, regional, and national regulations; avoid environmental release; record disposal details as part of compliance
Do Not Release: Prevent release into water, soil, or public sewers
UN Number: 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains 1,2,4,5-tetrachloro-3-nitrobenzene)
Hazard Class: 9
Packing Group: III
Marine Pollutant: Yes
Labeling Requirements: Environmentally hazardous materials (class 9)
Special Precautions: Transport in original container, clearly labeled; prevent damage or leaks; handle according to all applicable regulations
OSHA: Not regulated under specific OSHA standards
SARA Title III (Sections 302, 313): Listed under SARA 313 for toxic chemicals
TSCA: Listed on the U.S. TSCA Inventory
RCRA: Classifiable as hazardous waste
REACH: Subject to registration and restriction in the EU
Labeling requirements: Must display signal words, hazard and precautionary statements, supplier information
Other National/International Regulations: Environmental impact classification in many countries; export and import may require notification
Worker Protection: Employers must inform workers of hazards, ensure proper training and access to protective equipment
